اسلان كسيموف, ديمتري كابانوف

جامعة الملك عبدالله للعلوم والتقنية · السعودية

Detonation is a supersonic mode of combustion that is modeled by a system of conservation laws of compressible fluid mechanics coupled with the equations describing thermodynamic and chemical properties of the fluid. Mathematically, these governing equations admit steady-state travelling-wave solutions consisting of a leading shock wave followed by a reaction zone. However, such solutions are often unstable to perturbations and rarely observed in laboratory experiments.The goal of this work is to study the stability of travelling-wave solutions of detonation models by the following novel approach. We linearize the governing equations about a base travelling-wave solution and solve the resultant linearized problem using high-order numerical methods. The results of these computations are postprocessed using dynamic mode decomposition to extract growth rates and frequencies of the perturbations and predict stability of travelling-wave solutions to infinitesimal perturbations.We apply this approach to two models based on the reactive Euler equations for perfect gases. For the first model with a one-step reaction mechanism, we find agreement of our results with the results of normal-mode analysis. For the second model with a two-step mechanism, we find that both types of admissible travelling-wave solutions exhibit the same stability spectra.Then we investigate the Fickett’s detonation analogue coupled with a particular reaction-rate expression. In addition to the linear stability analysis of this model, we demonstrate that it exhibits rich nonlinear dynamics with multiple bifurcations and chaotic behavior.

Kebour Mohamed Nadjib Faouzi, Lounis Mohamed , خالد بومشدة

كلية التكنولوجيا-جامعة أمحمد بوقرة - بومرداس · الجزائر

محمد عماد سعدا, ندي خليفة

كلية التربية-جامعة دمشق · سوريا

Kecha Mouloud , سعاد مكي, فوزية مسيون

كلية العلوم الطبيعية والحياتية-جامعة عبد الرحمان ميرة - بجاية · الجزائر

e système HACCP est un des outils de l’assurance qualité qui définit, évalue et permet lamaitrise des dangers qui menacent la salubrité des aliments. Ils se déroulent en 14 étapesrésumées dans trois grandes phases:Préparer l’étude (Etape 1à6), Analyser les dangers (Etape 7,8 &9) et Formaliser l’assurancequalité &sécurité (Etape 10à14).Notre stage de 4 mois au niveau d`une unité de l’industrie laitière « DANONE AKBOU »,nous apermis une contribution à la mise en place du système HACCPen suivant la démarchede ce système appliqué lors de processus de fabrication de Yaourt étuvé ferme«Yaoumi» &Yaourt «Activia».Eneffet, trois types de danger (biologiques, chimiques et physiques) ont été déterminés et troisCCP & cinq PRPo ont été identifiés et qui ont exigéspar lasuite, lamise en place d’un systèmede surveillance pourleur maitrise. De plus nous avons validé la pasteurisation de quoi etcomment aprèsde nombreuses expériences réalisés.

محمد سميح شفيق شناعة, نعمان مالكية

جامعة القدس · فلسطين

Pregabalin is an anticonvulsant agent used for the peripheral and central neuropathic paintreatment, marketed as Capsule and Solution dosage forms. The purpose of this study is todevelop an immediate release Pregabalin Tablet, as a new dosage form in the Palestinianmarket that is bioequivalent to the FDA approved Reference Pregabalin Capsules (Lyrica).Pregabalin drug substance and the finished product during the time of development werenot described in either the British or US pharmacopoeia.The chemical and physical evaluation of bulk drug substance (Pregabalin) wasaccomplished following the manufacturer`s analytical method and specification. A newreversed-phase, isocratic LC method was developed and validated according to USPvalidation parameters, for the qualitative and quantitative determination of Pregabalin inpharmaceutical dosage forms using HPLC (LaChrome Elite) equipped with photodiodearray UV detector. Mobile Phase is a mixture of Phosphate Buffer pH 6.9, and acetonitrile(94:6).Chromatographic System is Column: C-18 ODS 5 to 10µm in diameter (25cm X 4.6 mmid), detector: UV set at wavelength 210 nm, Flowrate: 1.5 ml / min and Injection Volume:20 μL.Formula development was accomplished through a series of steps:Selection of excipients through compatibility studies, selection of manufacturing processand in-vitro comparison studies versus the reference product.Excipients compatibilities were studied by preparing a binary mixture of Pregabalin andexcipient (1:1) then sealed in neutral glass vials and incubated at 40±2 °C/75 ±5% RH for30 days. The mixtures were tested by means of FTIR for any possible interactions. Thefollowing excipients (Microcrystalline Cellulose, Pregelatinized Starch, Talc and MgStearate) were found to be compatible with Pregabalin.A series of pre formulation trials were composed and processed by direct compressionmethod. Selection of formula was based on:Powder characteristics: (such as compressibility ratio, flowability, bulk density and tappeddensity), which would allow for a simplified method of manufacture, friability, hardnessand disintegration of compressed tablets.The selected formulation was applied to prepare Pregabalin Tablets in two strengths, i.e.tablets containing 75mg/tablet and 300mg/tablet. They are prepared as dose weightproportional. The compressed tablets were film-coated with PVA based polymer by usingwater as solvent.The stability of film coated Pregabalin tablets were tested by incubating the finishedproducts in their final package (PVC-Alum) at different storage conditions i.e. 25 ± 2 °C /60 % ± 5% RH, 30 C ± 2 °C / 60% ± 5% RH and 40 C ± 2 °C / 75% ± 5% RH. Sampleswere tested biweekly for content of Pregabalin (assay), physical appearance, dissolutionrate, and degradation products.Pregabalin Tablets proved to be stable in all aspects for the period tested (1 month) at allstorage conditions.Biowavier study was performed between Pregabalin Tablets (75mg and 300mg) and theReference Pregabalin Capsules (Lyrica 75 and 300mg Capsules) using paddle methodrotated at 50 rpm in different dissolution media (0.06N Hydrochloric acid solution, Acetatebuffer pH 4.5 and phosphate buffer pH 6.8. It was found that either Reference or Testproducts release more than 85% of their Pregabalin content in 15 minutes. As PregabalinAPI, according to BCS is Class I drug and the dissolution profiles of Pregabalin Tablets issimilar to that of Reference Pregabalin Capsules (Lyrica) under the same test conditions,and all excipients used are not suspect of having any relevant impact on bioavailability it isstrongly believed that the developed Pregabalin Tablets are bioequivalent to the marketedLyrica Capsules.

Lilia Zinet , Ouarda Tidjet, Soualmia Abderrahmane

كلية العلوم الإنسانية والاجتماعية-جامعة عبد الرحمان ميرة - بجاية · الجزائر

Recherche consiste à connaître l'impact de la communication interne sur la motivation des salariés au sein de l'entreprise ALL PLAST sise à Akbou -Bejaia-

أميرة صياد, منيرة بوجلول, يوسف أوتفات

كلية الحقوق والعلوم السياسية-جامعة اكلى محند أولحاج - البويرة · الجزائر

جراب عبدالرزاق , محمد الأمين قرنين

كلية العلوم الإنسانية والاجتماعية-جامعة 8 ماي 1945 قالمة · الجزائر

Bouri Hadj, Nihel Khelifi

كلية الأداب واللغات-جامعة العربي بن مهيدي - أم البواقي · الجزائر

There is a recognized need for sophisticated pedagogy to come over the problems that encounter EFL students, and enhance their research writing performance. A growing body of evidence suggests the integration of genre analysis pedagogy, and research writing teaching. Most studies in the field of genre-based analysis have only focused on the rhetorical structure as their first aim. This study is exploratory in nature; it set out to discover if post-graduate students made use of the essential rhetorical moves of an abstract, and followed their succession, also it establishes the use of verb tenses, and verb choice along the abstracts. The analysis based on the five-move theory the IPMPrC proposed by Ken Hyland (2002) which was specially designed to examine the rhetorical structure of abstracts of articles. Admittedly, there was an examination of whether the abstracts include the essential moves with their sequential, or not in addition to identify the features that stood in each move; which are the tense, and the verb choice according to Hyland(2004). Evidence is presented which shows that most of post-graduate students did not follow, and include the essential moves, as well neither verb tenses nor verb choice. The result of these investigations suggests that there is a serious need for pedagogy-oriented abstracts, i.e. genre-based pedagogy.

Ahlem Maazouz, Sara Moussaoui, Sofiane Tchoketch Elkbir

كلية العلوم والتكنولوجيا-جامعة الدكتور يحيى فارس بالمدية · الجزائر

Ce mémoire est consacré à l’étude et la simulation du debruitage d’image par Les filtres classiques, les ondelettes et les curveletes, Pour éliminé le bruit dans la méthode des ondelettes par la méthode du seuillage des coefficients d'ondelettes.A la fin on fait une comparaison entre les techniques de débruitage de l’imagerie médicale