Mehdi Laghmari, نزهة الجلامي

كلية الطب والصيدلة - مراكش-جامعة القاضي عياض · المغرب

Guechoud Idir, Krouchi Fazia

كلية العلوم البيولوجية والزراعية-جامعة مولود معمري - تيزي وزو · الجزائر

Une étude structurale de l’if (Taxus baccata), une espèce rare en Algérie, a été envisagée au niveau de la station de Ain kechout, cédraie de Chréa, Atlas blidéen).Des placettes de 25x25m ont été délimitées au sein desquelles ont été examinés les paramètres structuraux de l’if (hauteur, diamètre et nombre de tiges) ; ceux du cèdre en tant qu’espèce dominante (hauteur, diamètres des tiges ; hauteur et diamètre du houppier) et ceux des autres ligneux du sous-bois (hauteur et nombre de tiges). Des paramètres stationnels ont été notés (degré de recouvrement, pente, altitude et orientation). Cette étude a été appuyée par un SIG qui a permis d’établir des cartes de distribution spatiale des individus d’ifs par classes de diamètre et de hauteur.Les résultats indiquent une préférence de l’if pour les couverts fermés. Préférence traduite par l’abondance des sujets de cette espèce ; leur port plus conservé et la présence d’une régénération.Bien que la régénération soit présente, des facteurs de perturbations susceptibles de mettre en péril la conservation de l’espèce sur le long terme ont été notés d’où la nécessité de renforcer les mesures sa conservation en vue de mieux protéger la régénération en place et de garantir des régénérations futures.

Samia Bouaziz-Cheradi, Hacène Ait Aider, Lina Roumane, Mahdi Cheradi, Mailika Massicilia Mokhtari

كلية هندسة معمارية-جامعة مولود معمري - تيزي وزو · الجزائر

اثير هشام مهدي التميمي, انتصار هادي حميدي الحلفي

كلية الزراعة-جامعة بغداد · العراق

أبوضار الحسن, عبدالله أشركي أفقير

كلية العلوم القانونية والاقتصادية والاجتماعية - طنجة-جامعة عبدالمالك السعدي · المغرب

Ait Bara Hani, Dalila Khiredinde, Melkhir Hammamouche

كلية العلوم الاقتصادية والتجارية والإدارة-جامعة عبد الرحمان ميرة - بجاية · الجزائر

Notre étude intitulé "Analyse de l'impact de la qualité des services sur la satisfaction etla fidélisation des clients - Cas de l'agence d'assurance SAA Bejaia" examine l'importance dela qualité des services dans la satisfaction et la fidélisation des clients. Les résultats de l'enquêterévèlent l'efficacité du traitement des réclamations et la nécessité de développer davantage lesoutils de fidélisation pour répondre aux attentes croissantes des clients. Des propositions sontformulées, notamment en matière de personnalisation des offres et de gestion des réclamations,pour améliorer la satisfaction globale des clients. L'agence SAA Bejaia est encouragée àmaintenir ses standards élevés et à offrir une expérience client exceptionnelle pour consolidersa position sur le marché et attirer de nouveaux clients tout en fidélisant sa clientèle existante.En adoptant ces recommandations, l'agence pourra assurer la satisfaction des clients, lesfidéliser et garantir son succès à long terme.

بوطي عزالدين, قدور هشام

كلية العلوم الاقتصادية والتجارية وعلوم التسيير-جامعة محمد خيضر - بسكرة · الجزائر

نويوة عبد المجيد

كلية الحقوق والعلوم السياسية-جامعة محمد خيضر - بسكرة · الجزائر

Ashly H. Pinnington, Meera Bin Hindi

كلية إدارة الأعمال والقانون-الجامعة البريطانية في دبي · الامارات

The Project Management Office (PMO) has recently become a vital business unit in many organizations worldwide and is critical to the success of project management functions in many organizations. This dissertation research has been developed with the aim of studying the roles and responsibilities of the PMO, and proposing the optimum PMO specification for the Ministry of Public Works in the UAE based on actual needs.The PMO has different roles and responsibilities, structure, staff numbers, and nature of roles and these factors often vary between organizations depending on the needs of organization itself. The roles of the PMO might be a supportive, coordinative or controlling role, and some organizations might have multiple PMOs with variance in their roles. The accurate identification of the PMO roles is important as some organizations might spend money and resources on establishing PMOs that don’t satisfy their needs and requirements.To achieve the objectives of this research dissertation, a qualitative research methodology that involved mixed approaches have been used including studying the different roles of the PMOs anddifferent practices worldwide and witin the UAE environment. The data collection uses resources available from Ministry of Public Works (MoPW), classifying the needs of MoPW based on Hill’s frameworks of PMO roles, and recommends a road map to establish a mature Project Management Office (PMO).The outcomes of this research show that the MoPW needs vary between the controlling, supporting, and coordinating requirements, which have been classified according to priority and linked to a road map based on a five years plan. It is divided into three stages to ensure that the PMO reaches the required maturity level and satisfiesy the UAE government’s needs and expectations.

Eslam Mohammed Gaber ElNebrisi, Murat Oz

كلية الطب والعلوم الصحية-جامعة الإمارات العربية المتحدة · الامارات

Curcumin is a polyphenolic compound isolated from the rhizomes of Curcuma longa. Curcumin has been demonstrated to have antioxidant, anti-inflammatory, and anticancer properties. Moreover, it has been shown to exhibit beneficial effects in the treatment of several neurodegenerative diseases including Alzheimer’s and Parkinson’s diseases. However, the molecular and cellular targets mediating the pharmacological actions of curcumin remain largely unknown. In this study, the effects of curcumin application on the functional properties of the nicotinic acetylcholine receptor, a prototype for ligand-gated ion channels were investigated. Using the two-electrode voltage clamp technique, the results showed that curcumin co-application caused a significant potentiation of the action of human α7-nicotinic acetylcholine receptors (α7-nAChR) expressed in Xenopus oocytes. Importantly, curcumin was found less effective on other nicotinic receptor subunit combinations and other members of ligand-gated ion channels. Curcumin significantly decreased desensitization of α7-nAChR suggesting that it acts as a type II PAM. High affinity-binding site for curcumin on α7-nAChR was also verified by molecular docking study. In the second part of this study, the neuroprotective effects of curcumin in an animal model of Parkinson’s disease were investigated. Stereotaxic micro-neurosurgery was successfully established (for the first time in our university) and used to induce the toxin based (6-hydroxydopamine; 6-OHDA) animal model of Parkinson’s disease. This was followed by testing the behavior of the animals, tissue collection, immunohistochemistry, striatal fiber density measurement, and stereological data analysis. Systemic administration of curcumin alleviated 6-OHDA-induced motor abnormalities and protected against substantia nigra pars compacta dopaminergic neuronal loss, through an α7-nAChRs-mediated mechanism. The protective effects of curcumin were completely reversed by the administration of the α7-nAChR-selective antagonist methyllycaconitine (MLA). In summary, the results of this study suggest that α7-nAChR-mediated activation is an important mechanism for the neuroprotective effects of curcumin in toxin-based (6-hydroxydopamine; 6-OHDA) animal model of Parkinson’s disease.