رسائل دكتوراة
English
2017
Characteristics of Sudanese Human Sperm with Normal and Abnormal Morphology in Infertile Couples (2011-2017)
القرشي محمد علي, طارق الحبوب عربي محمد, مأمون الحاج علي, ياسر محمد الحسن
كلية الطب-جامعة الجزيرة · السودان
A scientific determination of fertilization ability of the sperm can be made by motility, viability and morphological examinations that are called as potential fertility criteria. Some previous studies documented only the total morphological defect rates without including the morphologic subjects. As it is recorded in many studies, the success of IUI, ICSI and IVF depends mainly on the quality of the collected semen. The study was designed to determine physiochemical characteristics of human semen including the common types of semen abnormalities, normal and abnormal morphology, motion kinetics and dynamic parameters of sperm cells in Sudanese population.2) Determine the range of (TZI) and (SDI).3) Provide reference values of the normal dynamic sperm classes and sperm motion kinetics of motility: (VCL), (VAP), (VSL), (MAD), (ALH), (BCF), (LIN), (WOB) and (STR). A prospective case series study for 566 menof infertile couples who were requesting semen analysis was applied to those came to the ULTRALAB laboratory center main campus and ULTRALAB branch of the Sudan Assisted Reproduction Center (SARC), Khartoum, Sudan. Data collection was done for 20 months from April 1st, 2010 to December 31st, 2011.analysis of semen samples was done using Computer Assisted Semen Analysis (CASA). The study demonstrates that there are differences including physiochemical properties of semen, normality or abnormality of sperm morphology, dynamic and motion kinetics parameters of sperm between Sudanese population and other studies including WHO standards and some significant differences in the mean of semen volume per ml and concentration per million per ml of the normal and abnormal semen samples comparing to other standards. SDI and TZI were higher in overall semen as well as in abnormal semen samples. The Motility (PR + NP, %) in Sudanese population was significantly less than WHO standards for normal semen samples. Common semen abnormalities were oligoasthenoteratozoospermia, asthenoteratozoospermia and asthenozoospermia. There are differences including physiochemical properties of semen, normality or abnormality of sperm morphology, dynamic and motion kinetics parameters of sperm between Sudanese population and other studies including WHO standards.The mean values of the normal semen samples VCL (μm/s), VSL (μm/s), VAP (μm/s), MAD (degree), ALH (m/s), BCF (Hz), LIN (%), WOB (%) and STR (%) which reflect the fertilization ability of human sperm and act as indicators of sperm progression can be considered as standard reference values among Sudanese population.
