رسائل ماجيستير
English
2004
Pattern Of Bleeding Disorders Among Children In Khartoum State
INAAM NOURELDYME MOHAMMED, MOHAMED SIR .K. HASHIM
كلية الطب-جامعة الخرطوم · السودان
This is a descriptive hospital based study conducted in allKhartoum State Pediatrics Hospitals during the period from April2002 – October 2003 including 120 children.The main objectives were to determine the demographiccharacteristics and the clinical pattern of bleeding disorders.Further more, the study aimed to assess mothers' attitude towardscertain aspects of bleeding disorder.The mean age of children was 1.7±o.7 years with obviousmale predominance (75.8%). The majority of patients belong toShaygia (21.7%), Gaaleen (20.8%) and Bagara (18.3%) tribes.77.5%of patients belong to a low and moderate socioeconomicclasses.The main presenting symptoms were nasal bleeding(30%)followed by joint swelling and gum bleeding in (28.3%) and(19.2%) respectively. Muscular swelling and skin rash occurred in(17.5%) and(8.3%) respectively. while seven patients (5.8%)presented with bleeding following circumcision. Bleedingfollowing cut wounds , hematamesis and malena were lessreported. The majority of patients (43.4%) were affected with7Hemophilia A, 25 patients (20.8%) with (VWD)and 11 patients(9.2%) with Hemophilia B. Seven patients(5.8%) had (ITP), sixpatients(5%) had aplastic anemia, four patients(3.3%) hadhemorrhagic disease of the newborn while thrombasthenia affect(3.3%) and two patients were affected with factor VII deficiency.Only one patient was assumed to have factor XIII deficiency. Fivepatients died before reaching a final diagnosis.No significant correlation between mothers' attitude andthe social class of the family nor with their educational level. Theirattitude was mainly affected by the duration of illness as 88.5% ofmothers whose children had the disease for more than 10 yearstend to restrict certain activities such as football compared to11.5% who behave in over restriction or over permission way andin response to trauma 84.6% of them go immediately to hospital.76.4% of them know that certain drugs such as Asprin and use ofintramuscular injections should not b e given to their children aswell as 84.6% of mothers with positive family history of bleedingdisorder ( P- value0.05).