Counting of CD4 and CD8 T- Lymphocytes in Mycetoma Patients

الموضوعات

طب

الملخص

This study was carried in the period from December 2002 to February2003. A total of 49 blood samples werecollected from mycetoma patients inMycetoma Research Center – Soba Civil Hospital and National Healthlaboratory (ESTAC)- Khartoum State. The group surveyed included: 17(34.7%)infected untreated or new patients, 32 (65.3%)infected treated patients, andnormal control group (16 individual).The study showed that males were more affectedthan females and theratio was 4:1. Most of mycetoma patients werein the age group 15 – 25 yearsold. Students (20.4%), jobless (18.4%) and farmers (14.3%) were moreaffected than other occupations. Algazera State had a highest prevalence ofmycetoma with (34.7%); next state was Khartoum State (16.3%).The duration of the disease varied from 7 month to 30 years and theonsets of the disease in most of patients (73.5%) had no known history oftrauma. Left foot was the major site of infection (34.7%) and most of patients(83.7%) had no family history of mycetomainfection. Eumycetoma infectionhad higher prevalence (59.2%) than actinomycetoma infection (38.8%).The drug used for treatment in eumycetoma infection was ketoconazole,and in actinomycetoma was a combination of Streptomycin, Septrin and folicacid.Total white blood cells in most of patients (44.9%)were normal countbetween 4050 - 6000cells ⁄µl. and the mean value in untreated patients was6081.5cells ⁄µl, while in treatedpatients it was 6178.3cells ⁄µland in non-infected control it was 570.9 cells/µl. The mean value ofCD4 counts inuntreated patients was 664.7cells ⁄µl, while in treated patients it was 606.8cells⁄µl and was 1010 cells ⁄µlin non- infected control.The mean value of CD8iiicounts in untreated patients was 679.7cells ⁄µl,while in treated patients it was720.9cells/µland in non- infected control it was 639cells/µl.The mean values of differential counts of white blood cells in non-infected control group were 58%neutrophils, 39%lymphocytes, 2%monocytesand 1%esinophils.Differential counts of white blood cells, in untreated patients have themean value of neutrophils was 59%, lymphocytes 36%, monocytes 2%andesinophils 1%,while in treated patients the mean value of neutrophils was55%, lymphocytes 40%, monocytes 3%and esinophils 2%CD4 ⁄CD8 ratio in all patients was 1.1:1. In new and treated patients theratio was 1.2:1and in non – infectedcontrols it was 1.6:1.CD4 count was numerically higherin infected treated patients(710cells/µl) than infected untreated patients (664cells/µl). While CD8 count ininfected treated (719 cells/µl) was numerically lower thanin infected untreatedpatients (1378 cells/µl)

روابط وملفات

التعريف والنوع

رقم الوثيقة

ffbe9e43-67f5-4b30-96a7-0a08b19fb473

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

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أسماء الملفات

ffbe9e43-67f5-4b30-96a7-0a08b19fb473_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":"سليمان محمد الحسن","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"نازك محمد محمد المهدي","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

English

المصدر والدورية

اسم المصدر

Counting of CD4 and CD8 T- Lymphocytes in Mycetoma Patients

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

سليمان محمد الحسن

الإعداد

نازك محمد محمد المهدي

الاقتباسات الببليوغرافية