Novel cationic water solublepolynitrogen/copper (II) complexes as a new antimicrobial therapy

الموضوعات

علوم بحتة وطبيعية

الملخص

The six dicationic water soluble copper(II) complex1, complex2 complex3, complex4, complex5 and complex6, of general formula [CuNNN(NN)]Br2 [NNN = triamine and NN is chda = 1,2-diamiocyclohexane or Me2pn = 2,2dimethyl-1,3diamino propane] were prepared under ultrasonic mode with very good yield. These complexes were characterized by elemental microanalysis, UV-visible and IR spectroscopy.It was found that four complexes (complex1, complex3, complex4, complex5) of the six complexes have a high antimicrobial activity against Klebsiella, Escherichia coli, Proteus and Staphylococcus aureus. Complex2 have a little antimicrobial activity. Complex6 have not any antimicrobial activity at any kind of the used bacteria, this could be because the complex is unstable.The antibiotic Cephalexin was used as a standard to compare the antibacterial activity of the six complexes against the bacteria. Cephalexin used as antibacterial drug to kill Gram-positive and Gram-negative bacteria. The antibacterial activity of the complexes1,3,4,5 against the bacteria were better than Cephalexin. Also the complexes 1,3,4,5 showed a high antimicrobial activity against Klebsiella compared with Cephalexin that have not any antibacterial activity against this kind of bacteria, which encourages to use these complexes as a topical treatment instead of Cephalexin.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0ee2118e-7a92-43c7-92e7-804c39e5805a

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

47889_1.pdf

بيانات النشر

ترجمة العنوان

تحضير معقدات نحاس أيونية مبتكرة واستخدامها كمضادات لمبكتيريا المقاومة لممضادات

ألقاب المؤلفين

[{"name_ar":"أشرف صواقطة ","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"اسماعيل وراد","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"معاذ رباح جمال عامر ","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

English

المصدر والدورية

اسم المصدر

Novel cationic water solublepolynitrogen/copper (II) complexes as a new antimicrobial therapy

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

أشرف صواقطة , اسماعيل وراد

الإعداد

معاذ رباح جمال عامر

الاقتباسات الببليوغرافية