Analysis Of The Wolbachia Endosymbiont Effects On Their Drosophila Melanogaster Host

الموضوعات

علوم بحتة وطبيعية

الملخص

Wolbachia is a known endosymbiont of many insects including the fruit fly Drosophila melanogaster and the disease vectors Culex pipiens and Aedes albopictus. It is present in the gonads and induces cytoplasmic incompatibility; a partial one in Drosophila and a complete one in mosquitoes. Therefore, understanding how this microbe manipulates its host to induce this reproductive alteration would be of great importance. It would indeed fill in a gap in knowledge present in the field pertaining to the nature of this interaction: is Wolbachia perceived as a parasite by the host? Does its presence impose some sort selective advantage or disadvantage on its host's fitness? Moreover, deciphering the sequence of events leading to cytoplasmic incompatibility would indeed open new possibilities for biological control of some disease vectors, of which an example of would be the introduction of infected males to an environment of Wolbachia free females, leading to cytoplasmic incompatibility and thus population control. In this study we aim to understand some of the mechanisms employed by Wolbachia to manipulate its natural host Drosophila melanogaster, and how in turn does this fly counteract and respond to the bacterium studying the immune responses activated by Drosophila specifically. In this study, we use the genetic tools available for Drosophila in order to tackle the interactions taking place at the molecular levels between the endosymbiont and its host. We try to address how the bacterium is manipulating its host at the molecular and gene levels, and in turn check how the host is responding to control Wolbachia.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0ea777bb-badd-436b-bb10-a2912d0d5ac6

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1632822_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":"حسان علي مصطفى ","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"زكريا كمبريس","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

Analysis Of The Wolbachia Endosymbiont Effects On Their Drosophila Melanogaster Host

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

زكريا كمبريس

الإعداد

حسان علي مصطفى

الاقتباسات الببليوغرافية