دور مناسب الصفيحات -حجم الصفيحات الوسطي و معدل توزع الصفيحات- في التشخيص السببي لنقص الصفيحات

الموضوعات

طب

روابط وملفات

التعريف والنوع

رقم الوثيقة

0b66c336-4c83-4e03-bd99-20d6a849d273

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1959391_1.pdf

بيانات النشر

ترجمة العنوان

The Role of Platelets indices -Mean Platelet Volume MPV , Platelet Distribution Width PDW- in the diagnosis of Thrombocytopenia

ألقاب المؤلفين

[{"name_ar":" فراس حسين","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"ايهاب محسن صالح","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

دور مناسب الصفيحات -حجم الصفيحات الوسطي و معدل توزع الصفيحات- في التشخيص السببي لنقص الصفيحات

المحتوى والصفحات

عدد الصفحات

71

ترجمة الملخص

Introduction: Thrombocytopenia is considered to be a common complain of outpatients and hospitalized ones, ranging from asymptomatic to severe death causing hemorrhage. Diagnosing thrombocytopenia depends mainly on study of bone marrow which is an invasive process. Complete blood count on automated hematology analyzers is widely used nowadays with no extra cost, and platelets indices are part of the blood profile and less often used in diagnosing thrombocytopenia.Aim of the study:To determine the agreement between the the study of bone marrow as a gold standard test and the platelets indices as a new test. And to study the differences between two groups of patients classified using the gold standard test.Methods: a random sample of 109 patients in Tishreen University Hospital in Latakia City between 2017 and 2018 with thrombocytopenia. thrombocytopenia was defined as platelet count under 150×109/liter. A peripheral blood smear was performed to confirm. Patients with a history of drugs affecting platelets or having chemotherapyand radiotherapywere excluded.Results: 55 patientshad hyperdestructive thrombocytopenia and 54 patients had hypoproductive thrombocytopenia, Mean Platelet Volume in hyperdestructive and hypoproductive groups was 9.6 and 8.5 respectively, and the difference was statistically significant p=0.0014. An agreement test was carried out between the gold standard test which is the study of the bone marrow and the platelets indices as the new test. The agreement with MPV was 80% and the strength was very good. While the agreement with PDW was 50% and the strength was moderate.

كلمات الباحثين

Mean Platelet Volume (MPV), Platelet Distribution Width PDW, Thrombocytopenia, حجم الصفيحات الوسطي MPV, معدل توزع الصفيحات PDW, نقص صفيحات الدم thrombocytopenia

إشراف وإعداد

الإشراف

فراس حسين

الإعداد

ايهاب محسن صالح

الاقتباسات الببليوغرافية