Assessment of Thyroid Function in Relation with Phosphate Calcium Ratio in Traditional Gold Mininers in Northern Sudan
الطيب محمد عبد الرحمن الطيب, محمد عبدالله محمد محمد احمد
كلية الدراسات العليا والبحث العلمي-جامعة الرباط الوطني · السودان
Objective of the study: The aim of this study was to assess the thyroid functions, and the calcium/phosphate ratio in traditional gold miners in the River Nile State- Sudan. Material and methods: blood samples were collected from 83 Sudanese miners working in traditional mining sites in the River Nile State, their ages ranged from 18 -55 years, and 50 healthy volunteers from Khartoum State, as control group. Serum calcium and phosphorous were measured using automated chemical analyzer (Mindray BS-200 China). Thyroid hormones were measured using enzyme linked immune-sorbent assay (ELISA). Data were analyzed using IBM SPSS Statistics version 20. Results: The study revealed that the mean ±SD of calcium and phosphorous in the gold miners was (9.4± 0.50, 4.1± 0.80 mg/dl) respectively while; it was (9.3± 0.57, 3.1± 0.82 mg/dl) respectively in the control group. There was a significant increase in serum phosphorous levels in traditional gold minor when compared with their control group. The mean serum levels of TSH, TT3, FT3, TT4 & FT4, among gold miners was (5.1, 1.16, 1.3, 86 and 6.4 respectively); versus (2.4, 1.47, 3.1, 72.6 and 12.5 and respectively) in the control group. There was a significant decrease in serum TT3, FT3 and FT4 when compared to their control (P.value= 0.004, 0.000, 0.000) respectively; while there was a significant increase in serum TT4 and TSH (P.value= 0.002, 0.000 respectively). Conclusion: Traditional gold miners working effects the thyroid function and also effect in the phosphorous level.