سعاد حافظ مهدي, صالح مهدي عداي المعموري

كلية التربية للعلوم الإنسانية-جامعة بابل · العراق

بن دحمان مينة, خضرة شتوح

كلية الاداب واللغات-جامعة محمد بوضياف - المسيلة · الجزائر

ترتبط الرواية الجزائرية ارتباطا وثيقا بنبض الإيقاع الداخلي للحياة في أبسط صورها وأعقد تجلياتها، فتحمل بذلك أحاسيس الإنسان الجزائري وانفعالاته وانشغالاته بقضاياه اليومية والمصيرية في مجالات السياسة والاجتماع، وتجسد إعاقاته بالسلطات المختلفة التي تكبل طاقاته وتشمل تطلعاته.وتستثمر الرواية لغة البوح والاعتراف بما يعتمل في الذات من هواجس وتصوّرات بانية بذلك أفقها الجمالي على أساس كتابة روائية تصفي إلى همس الشارع الجزائري وفوضاه وقلقه العاري.

نجاح صالح هادي الزهيري, هاله محمد سعيد

كلية التربية للعلوم الانسانية-جامعة ديالي · العراق

Ayesha Banu, Mohammad Farhan

كلية العلوم الصحية والحيوية-جامعة حمد بن خليفة · قطر

Feeding is a fundamental and defining behavior of heterotrophic organisms and its regulation is important for the fitness of an animal. Serotonin, a master modulator, mediates internal states, modifies existing neural circuits, and regulates multiple behaviors including feeding across all animal species, including humans and fruit flies. However, an in-depth study on the neuromodulatory effects of serotonin on feeding and related behaviors has been held back for several technical reasons. In this work, we used optogenetics and genetic methods to study the systemic effect of serotonin related manipulations on ongoing feeding behavior. We analyze the finer details of the feeding pattern of these flies – also called the feeding microstructure – to elucidate the subtle changes in the feeding aspects controlled by serotonin. We delve into the modulation of this microstructure in different hunger states. We also study the behavior within the context of locomotion and touch upon the differences in feeding aspects in the free and restrained state. We show that serotonin affects multiple parameters in a state-dependent manner and regulates the behaviors differently under a free and restrained state of the animal. We elucidate the role of serotonin receptors in feeding and show that different receptors promote and suppress feeding. We further investigate how chronic alterations in serotonin release from central serotonergic cells may affect the insulin production from brain insulin producing cells and alter the fat storage in the abdominal fat body and visceral organs like intestines.

امال عمرات موسى, زهراء هادي علي , كرار كاظم محسن

كلية الصيدلة-جامعة كربلاء · العراق

Breast cancer is considered a global problem of health that affects the breast. Tamoxifen which is non-steroidal selective estrogen receptor modulator. It is considered standard adjuvant therapy and widely used endocrine therapy for a patient with steroid hormone receptor-positive breast cancer. CYP2C19 plays an essential role in forming a proportion of tamoxifen metabolites including converting 4-OH-tamoxifen to endoxifen. Pharmacogenomics studies the impact of the individual’s genome on response to medication and describes how genes influence the metabolism of drugs. Aims of the study: The aim of present study is to identify the single nucleotide polymorphism of (G >A, rs4986893) and (C >T, rs11188072) in a sample of Iraqi breast cancer women and to investigate the effect of CYP2C19 genetic polymorphisms on tamoxifen therapy response. Patients and methods: This is across-sectional observational study carried out at Imam AL-Hussein Medical City/Oncology center in kerbala and laboratories of College of Pharmacy / University of Kerbela . The study was conducted on total 100 females Iraqi women aged 45-65 years with (Esterogen and /or Progesteron- receptor positive breast cancer, taken tamoxifen tablet 20 mg daily dose at least 3 months were included without any diseases.

Younes Halliche, Hilal Boukrif, Karima Sisalah, Sabrina Larbani

كلية العلوم الاقتصادية والتجارية وعلوم التسيير-جامعة مولود معمري - تيزي وزو · الجزائر

Aicha Tsouri Ben Tsouri, H.Takabait, L.Saadi , Meriem Benkhaoua

كلية علوم الطبيعة والحياة-جامعة سعد دحلب - البليدة · الجزائر

La meilleure compréhension de l’aspect morphologique et moléculaire de l’hépatoblastome est très importante pour diagnostiquer plus précisément la maladie, ainsi que pour développer des nouvelles approches thérapeutiques. Ce présent travail a pour objectif d’étudier les types histologiques de l’hépatoblastome et de rechercher d’une part la corrélation entre le taux sérique de l’Alpha-fœtoproteine et son intensité selon les différents sous-types histologiques. D’autre part rechercher la localisation de la s-caténane et son intensité dans les différents sous-types histologiques .Afin d’atteindre cet objectif, nous avons mené une étude sur 30 patients atteints d’hépatoblastome, dans une période de 8 mois, de février a septembre 2017. Nous avons utilise les techniques Hématoxyline- éosine et immunohistochimie. Les résultats obtenus démontrent que l’hépatoblastome est une tumeur rare survenant surtout chez le petit enfant (avant l’Age de 3 ans), avec une prédominance de sexe masculin. Le dosage sérique d’Alpha-fœtoproteine indique que son taux est élevé (<100 ng/mL) dans plus de 90% des cas de différentes classifications histologiques, tandis qu’il est faible dans les cas présentant une histologie indifférenciée a petites cellules. L’immun marquage de cette molécule indique qu’il n’existe aucune corrélation entre son taux sérique au moment du diagnostic et son expression dans les tumeurs étudies. L’immun marquage de la A-caténane montre que cette molécule est exprimée dans la majorité des cas, ce qui indique son importance dans la tumorigenese de l’hépatoblastome. D’apres ces résultats, nous pouvons conclure que le dosage sérique de l’Alpha-fœtoproteine est un examen essentiel pour le diagnostic et le pronostique de l’hépatoblastome et que la A-caténane est un outil axillaire dans son diagnostic.

نغم أديب

الجامعة التكنولوجية · العراق

عبدالمنعم اعبيد, هادي شندول

كلية الهندسة-جامعة طرابلس · ليبيا

The digital photomaps which e produced from digital aerial photos have be prested in some detail in resech work. This thesis focuses mainly on producing a rectified photomap and accuracy assessmt of ground check point’s coordinates that e distributed in the chos study ea within a local region which has be used to develop a digital photomap for the urbanized Proposed study ea that is located at a pt of Tripoli City (anofle region).Consequtly, such as urbanized ea the effect of tilt and relief displacemt must be considered in the rectification mathematical model. Due to the rapid developmt in extding an urbanized eas which forms the major problem in developing countries where a lack of up-to-date digital lge scale photomap which can be obtained with save money and effort to produce useful information for purpose urban planning . The Digital airborne imaging systems integrated with in-flight control systems consisting of Global positioning system (GPS) and inertial measuremt units (IMU) that e used to provide the data needed to assist a rectification mathematical model to obtain a rectified digital photomap. Consequtly, the thesis investigates the pottial of using integrated ssors with a number of ground control points to produce a rectified photomap for study ea which contains thirte Digital images acquired from airborne digital camera at flight height 1100m which is main point for the contribution in the study (combination photogrammetric solution); consequtly, the procedure is depdt on a compison betwe result of photogrammetric solutions, which e obtained through direct and indirect approaches against a combined photogrammetric solution. To achieve and obtain usefulness information, twty shped and well distributed check points e chos on the study ea that e used to know the quality of the RMSE in planimetry and elevation at check points according to the adopted Map Standds Accuracy that e worked in surveying deptmt of Libya (SDL), Some good results have be achieved in the study. Since by analyzing the result, which is found that the combination photogrammetric solution that have be giv best result with respect to the geospatial accuracy, and which was chos to produce a rectified photomap of digital aerial images for study ea that e found the produced rectified photomap satisfied the theoretical lge scale mapping of 1:1,000 according to the followed Map Standds Accuracy (SDL).

حفصة كوييبي, خيرة زبوج, زهرة مرجاوي

كلية العلوم الاجتماعية-جامعة عبد الحميد بن باديس مستغانم · الجزائر