مخطاري خالد, غاني محمد, نبيلة رميلي
معهد علوم وتقنيات النشاطات البدنية والرياضية-جامعة أحمد بن يحيى الونشريسي - تيسمسيلت · الجزائر
حسين عجلان حسن, عبدالكريم ياسين أسود الفارس العزاوي
جامعة سانت كليمنتس العالمية - العراق · العراق
El Fadil Elobied Omer, EL-Nour El-Amin Abdelrahman, Nagla Mohamed Ahmed Mohamed
كلية المختبرات الطبية-جامعة النيلين · السودان
BackgroundCancer patients have a high risk of fungal infections, especially by Candida species. Non-C. albicans Candida infections and less common yeast infections have been increasing in recent years. Identification by conventional methods can be difficult and sometimes inconclusive.AimThis study aimed to detect the prevalence of oral yeast species among cancer patients attended to Isotope and Radiation Center during the period from April 2013 to December 2017.MethodsThe study involved 333 cancer patients with Mean age of 48 years (168 patients under treatment [study group] and 165 patients before treatment [control group]. Oral swabs were collected from all patients. Urine (n=9) or sputum (n=14) specimens were collected from patients under treatment showing clinical features of urinary tract infections (UTI) or lower respiratory tract infection, respectively. All specimens (n=356) were cultured without delay in Sabouraud's dextrose agar plates (SDA). Internal Ttanscriped Spacer (ITS1 and ITS2) region of isolated yeast were amplified by PCR and sequenced. The obtained sequences were compared to reference sequence available in the GenBank database using BLAST.Results:Culture results showed oral yeast species were isolated from 69/168 (41.1%) and 74/165 (44.8%) of patients among study and control groups, respectively (P value > 0.05). High frequency of yeast isolates were detected among females, in-patients, breast cancer, with chemotherapy treatment, and among those who were from North Sudan and South Dar-for. Sequence analysis showed, C. albicans to be the most prevalent organism (93; 52.5%) followed by C. tropicalis (29; 16.4%), and C. glabrata (24; 13.6%). Non-C. albicans Candida and uncommon rare yeast were found to be associated with oral infections and colonization among the study and control groups, whereas C.albicans was the most common species (66.7%) associated with oral candidiasis among the treated patients. The highest rate of Fluconazole resistance was observed in C.albicans (51.6%) followed by Pichia .kudriavzevii (Teleomorph of Candida krusei) (37.5%) and C. tropicalis 13%.Conclusion:Cancer patients were highly colonized with different oral yeast species, which indicates that ITS sequence analysis is an accurate method for identification. This will aid effective management to prevent dissemination of disease especially among those who are under chemo and/or radiotherapy treatment.الخلاصةخلفية الدراسة:مرضى السرطان لديهم مخاطر عالية للتعرض للإلتهابات الفطرية خاصة لأنواع فطر المبيضات.في السنوات الأخيرة زادت الإصابة بفطر المبيضات غير البيضاء والخمائر الأقل شيوعاً، والتعرف عليها بالطرق التقليدية من الصعوبة وعدم الدقة بمكان.الهدف:لقد هدفت هذه الدراسة لإيجاد مدى شيوع أنواع الخمائر الفمية من بين مرضى السرطان الوافدين لمركز العلاج بالأشعة والطب النوي في الفترة مابين ابريل 2013 إلي ديسمبر 2017.الطرق:تضمنت هذه الدراسة عدد 333 مريضاً بالسرطان بمتوسط أعمار 48 سنة. وهم عبارة عن مجموعتين(168 مريض تحت العلاج عبارة عن مجموعة الدراسة و165 مريض قبل بداية العلاج عبارة عن مجموعة التحكم).لقد تم جمع عينات عبارة عن مسحات فمية من كل المرضي بالإضافة لعينات البول أو البلغم التي تم جمعها من المرضي الخاضعين للعلاج وكانت لديهم أعراض إلتهابات المجاري البولية أو أعراض الجهاز التنفسي الرئوي.لقد تم تزريع كل العينات المجموعة (356 عينة) في سط السابرود بدون تأخير. وتم التعرف علي الفطريات المعزولة بطريقة تحليل التسلسل الجيني لمنطقة النسخ الداخلية 1و2 للفطريات. (ITS1 and ITS2) بعد أن تم تضخيمها بواسطة جهاز تفاعل البلمرة المتسلسل (PCR), ولقد تمت مقارنة نتائج التسلسل الجيني المستلمة مع نتائج التسلسل الجيني المرجعية المتاجة والمودوعة في قاعدة بيانات بنك الجينات وذلك بأستخدام أداة بحث المواءمة الأساسية المحلية BLAST.النتائج:لقد أظهرت نتائج التزريع بأنة قد تم عزل أنواع الفطائر الفمية من 69 مريض من بين 168 مريض بنسبة 41,1% بمجوعة الدراسة ومن 74 من بين 165 مريض من مجموعة التحكم بنسبة 44% وهذة النسبة إحصائياً لايعتد بها. (0486p=0.)
ابتسام طالبي , بورتان عمر
كلية الاداب واللغات-جامعة اكلى محند أولحاج - البويرة · الجزائر
Bensayah Amel, M.K.Mendaci
كلية العلوم والعلوم التطبيقية-جامعة العربي بن مهيدي - أم البواقي · الجزائر
Ce projet nous permet de concevoir et réaliser un système commande et de contrôle de vitessede moteur à courant continu à l’aide de la carte arduino uno.La programmation de ce contrôleur est basée sur le langage C.Le circuit de puissance de commande utilise le pont H de type L298.Les résultats de la pratique sont similaires à ceux de la simulation
Aya Zineb Maarouf, Lahmer Mokhtaria, Raounak Lamouri
كلية اللغات والاداب-جامعة ابن خلدون – تيارت · الجزائر
بوعزة عبد القادر, خديجة لعروسي, سهام براح, مسعودة دحان
كلية العلوم الاقتصادية، التجارية وعلوم التسيير-جامعة أحمد دراية - أدرار · الجزائر
سهاد هادي محمد , نوار شامل طاهر
كلية العلوم الطبية التطبيقية-جامعة كربلاء · العراق
Viral hepatitis, which is an infection of the liver that results in its inflammation and damage, has been considered as global health problem for a very long time and is still regarded as a serious threat to human health. Hepatitis B virus (HBV) and Hepatitis C virus (HCV) can cause both acute and chronic infections. Cirrhosis is an important cause of morbidity and mortality among patients with chronic liver disease. The major etiologies of cirrhosis are HBV and HCV infections. Globally, among individuals with cirrhosis, 42% had an HBV infection and 21% had an HCV infection. It has been documented that as liver disease progresses, its ability to perform immune functions becomes impaired, allowing greater translocation of gut-derived microbes into systemic circulation and heightened susceptibility to systemic bacterial infections. Microbial products, such as lipopolysaccharide (LPS), is thought to be both a consequence of and promote liver disease progression. There is limited information regarding the association between circulatory LPS and the level of some inflammatory and anti-inflammatory cytokines, the type of liver disease, and disease severity. Thus, the aim of the current study was association between bacterial LPS (as marker for bacterial translocation) and type of liver disease (HBV, HCV, and liver cirrhosis). Across-sectional study was carried out at the College of Applied Medical Sciences/ Department of Clinical laboratories from the period 1 November 2022 to March 2023. Blood sample was collected from 89 patients with HBV, HCV, liver cirrhosis to be used in LPS, IL-1, and IL-10 measurement by ELISA technique. Out of 45 (50.56%) of patients were infected with HBV, 21 (23.59%) infected with HCV and 23 (25.84%) with liver cirrhosis, the mean age of the patients with HBV, HCV, and Liver cirrhosis were 39.84±16.823, 42.76±15.59, and 49.87±15.9 respectively. Significant difference was noticed between mean age of HBV and Liver cirrhosis. The highest frequency of HBV, HCV, and cirrhosis was noticed within age range between 20-39 years old. More than 75% of patients were suffer from chronic diseases and a significant difference in the mean age of acute and chronic infection was observed. No significant difference among the three studies groups were noticed according to Sex with M/F Ratio (29/16,1.8), (12/9,1.3), (10/13, 0.76) for HBV, HCV, and Liver cirrhosis respectively. The current study revealed a significant decrease in the mean levels of LPS, IL-1, and IL-10 between HBV and the other two study groups. Also, a positive significant correlation between LPS, IL-10, and IL-1 among the three studied groups of patients. Regarding diseases chronicity, the current study revealed that there were no significant differences in LPS, IL-1, and IL-10 levels according to disease duration. However, the mean level of LPS, IL-1, and 1L-10 were higher during the first year of the disease and the mean were higher in acute HBV than chronic HBV. This study indicated that there were, no significant variations in the mean levels of ALT, AST, ALK, PT, and TSB among HBV with HCV and liver cirrhotic patients. Approximately 53.5%, 33.3%, and 55.5% of HBV, HCV, and liver cirrhosis patients had an AST/ALT ratio greater than 1. Also, there was a significant positive correlation between LPS, IL-1, and IL-10 and alkaline phosphatase. The significantly lower mean of LPS, IL-1, and IL-10 in HBV infected patients reflects the impact of HBV or its component in manipulating the inflammatory immune response during infection, which impedes pathogen clearance and results in persistent infection. A significant correlation between LPS and IL-10 and IL-1 indicated that LPS might possibly induce and amplify the inflammatory response among the studied groups.
القحطاني فهم, بن لوكيل رمضان
كلية العلوم الاقتصادية والعلوم التجارية وعلوم التسيير-جامعة الجزائر 3 - إبراهيم سلطان شيبوط · الجزائر
حاولنا من خلال هذه الأطروحة دراسة أثر اختلاف الأجور في سوق المنافسة الكاملة على الاستثمار الأجنبي المباشر في المملكة العربية السعودية خلال الفترة 1994-2016، حيث قمنا أولا بدراسة قياسية لاختبار العلاقة بين الأجور والاستثمار الأجنبي المباشر، بعدها قمنا بإضافة معدل التضخم، والادخار، والناتج الداخلي الخام، ومعدل البطالة لنرى مدى مساهمتها في تأكيد العلاقة بين الأجور والاستثمار الأجنبي المباشر، لنتمكن في الأخير من الإجابة على الإشكالية المطروحة وهي ما مدى تأثير الأجور على جذب الاستثمار الأجنبي المباشر في المملكة العربية السعودية؟ وما هي العلاقة بينهما؟
Abubakr Hassan Atta Almola, Ismaiel Ali Hassab Al-Rhassol Mohammed, Shams Eldein Mohammed Ahmed
كلية علوم المختبرات الطبية-جامعة الجزيرة · السودان
Important one of the Malaria-associated hepatic dysfunctions are complications of malaria and are increasingly becoming problem of great concern in malaria endemic countries like Sudan. This was hospital based comparative cross-sectional study conducted in Al-Hassahisa Teaching Hospital from December 2014 to May 2015. The aim of this study was to evaluate the effect of malaria parasite density on liver function tests. This study included 50 individuals with positive falciparum malaria parasites.Two specimen containers were used for each subject. Anticoagulant containers, containing k2EDTA for malaria parasite test and plain containers for liver functions test.Then the degree of parasitaemia calculated and determined. The serum aspartate transaminases (AST), alanine transaminases (ALT), alkaline phosphatase (ALP), total and direct biliurbin, and urine urobilinogen were investigated in 50 individuals comprising both sexes. The results showed a significant difference {P. 0.05 } . The results concluded that serum AST, Total biliurbin, Direct bilirubin, and urine urobilinogen increasining with incrase malaria parasite density.
