قلة الكريات كمؤشر على الاصابة بدوالي المري عند مرضى تشمع الكبد
Introduction and The research aims The rate of progression of esophageal varices in patients with liver cirrhosis is ranging from 35% to 80%, and the risk of the initial bleeding from it is 25% to 35% within two years from their occurrence, and as a result has been the development of recommendations in order to conduct a survey for esophageal varices endoscopically for all patients with newly diagnosed cirrhosis of the liver[1], Numerous studies have emerged in order to search fornon-invasive methods in order to predict the presence of esophageal varices. Our study aimed to verify the ability of each of the platelet count, WBC counts, spleen diameter, Portal vein diameter to predict the development of esophageal varices.Material and methodThe study included 145 patients, frompatients admitted or auditors to the Aleppo university hospital, within the period from 24/06/2013 to 24/06/2014, whose age greater than 18 years old, and they have cirrhosis, and weexcluded patients diagnosed with esophageal varices previously. We take aclinical history, and a physical examination, laboratory analysis, radiograph examinations, and upper gastrointestinal endoscopyhas made. The results were analyzed and studied statistically.ResultsWe found that there is a correlation betweenthe appearance of esophageal varices andeach of the age, ascites, Child-Pughclassification, platelet counts, spleendiameter, portal vein diameter. Each of the platelet count, spleen diameter haveability to predict the presence of esophageal varices, and that the average white blood cell counts were lower in the presence of esophageal varices but the difference was not statistically significant.Best predictor was the platelet count and the best Cut-off point was 129 109/L (0.912 AUC, 100% Sensitivity, 80.65% Specificity, 95% PPV, 100% NPV), followed by the spleen diameter withbest Cut-off point 120mm (0.761 AUC, 96.49% sensitivity, 35.48% Specificity, 84.6%PPV, 73.3 NPV).Conclusion We found that the lower of white blood cell counts did not have statistical significance with the presence of esophageal varices, while both of thrombocytopenia and spleen diameter have the ability to predict the presence of 86esophageal varices. When the platelet count<129 109/L or spleen diameter >120mm we expect the presence of esophageal varices
عبداللطيف قصاص, محمد بشر أبودان
كلية الطب البشري-جامعة حلب · سوريا
الموضوعات
طب
روابط وملفات
التعريف والنوع
- رقم الوثيقة
- ff580da6-24ac-473d-b3d7-d42bd0f6822e
- رقم العقد
- 0
- نوع الوسائط
- Crawler
- نوع المحتوى
- الرسائل العلمية
- صيغة المصدر
- رسائل ماجيستير
- نوع الملف
- pdf text
- أسماء الملفات
- 1966175_1.pdf
بيانات النشر
- ترجمة العنوان
- Introduction and The research aims The rate of progression of esophageal varices in patients with liver cirrhosis is ranging from 35% to 80%, and the risk of the initial bleeding from it is 25% to 35% within two years from their occurrence, and as a result has been the development of recommendations in order to conduct a survey for esophageal varices endoscopically for all patients with newly diagnosed cirrhosis of the liver[1], Numerous studies have emerged in order to search fornon-invasive methods in order to predict the presence of esophageal varices. Our study aimed to verify the ability of each of the platelet count, WBC counts, spleen diameter, Portal vein diameter to predict the development of esophageal varices.Material and methodThe study included 145 patients, frompatients admitted or auditors to the Aleppo university hospital, within the period from 24/06/2013 to 24/06/2014, whose age greater than 18 years old, and they have cirrhosis, and weexcluded patients diagnosed with esophageal varices previously. We take aclinical history, and a physical examination, laboratory analysis, radiograph examinations, and upper gastrointestinal endoscopyhas made. The results were analyzed and studied statistically.ResultsWe found that there is a correlation betweenthe appearance of esophageal varices andeach of the age, ascites, Child-Pughclassification, platelet counts, spleendiameter, portal vein diameter. Each of the platelet count, spleen diameter haveability to predict the presence of esophageal varices, and that the average white blood cell counts were lower in the presence of esophageal varices but the difference was not statistically significant.Best predictor was the platelet count and the best Cut-off point was 129 109/L (0.912 AUC, 100% Sensitivity, 80.65% Specificity, 95% PPV, 100% NPV), followed by the spleen diameter withbest Cut-off point 120mm (0.761 AUC, 96.49% sensitivity, 35.48% Specificity, 84.6%PPV, 73.3 NPV).Conclusion We found that the lower of white blood cell counts did not have statistical significance with the presence of esophageal varices, while both of thrombocytopenia and spleen diameter have the ability to predict the presence of 86esophageal varices. When the platelet count<129 109/L or spleen diameter >120mm we expect the presence of esophageal varices
- ألقاب المؤلفين
- [{"name_ar":"عبداللطيف قصاص","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"محمد بشر أبودان","title_ar":"اعداد","title_en":"Preparation"}]
- اللغة
- Arabic
المصدر والدورية
- اسم المصدر
- قلة الكريات كمؤشر على الاصابة بدوالي المري عند مرضى تشمع الكبد
المحتوى والصفحات
- عدد الصفحات
- 0
- كلمات الباحثين
- الاصابة بدوالي المري, قلة الكريات, مرضى تشمع الكبد
إشراف وإعداد
- الإشراف
- عبداللطيف قصاص
- الإعداد
- محمد بشر أبودان
الاقتباسات الببليوغرافية
APA
MLA