دراسة مستويات 25 هيدروكسي فيتامين د 3 لدى مرضى سرطان الثدي المشخصين حديثا

الموضوعات

طب

روابط وملفات

التعريف والنوع

رقم الوثيقة

fc91f45f-21c4-4f59-bd72-c88afa405bae

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1964656_1.pdf

بيانات النشر

ترجمة العنوان

Serum 25 Hydroxy Vitamin D3 Among Newly diagnosed Breast Cancer patients

ألقاب المؤلفين

[{"name_ar":"سامر عاقل","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"فيصل رضوان","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"مضر يسري شيبان","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

دراسة مستويات 25 هيدروكسي فيتامين د 3 لدى مرضى سرطان الثدي المشخصين حديثا

المحتوى والصفحات

عدد الصفحات

0

ترجمة الملخص

Introduction :Breast cancer places second among the most cancers diagnosed worldwide (after lung cancer), and first among the women. Considering that comes vitamin D as an anti-cancerous potential factor, supported by a lot of studies and articles worldwide that describe his relationship with cancer in general and breast cancer in specific , and this study comes in the context of highlighting the vitamin D and to expand the framework of a research on one of the most common cancers, breast cancer .Objective:To compare serum levels of vitamin D among women with breast cancer and healthy women within the Syrian coast area. Research methods: Study sample was divided into two groups: the first is breast cancer patients, newly diagnosed (before starting any treatment) and auditors to Tishreen University hospital / Oncology Department in Latakia, and with diagnosis confirmed histologically (N = 58) during the last three months of 2014, The second group (control group) is the group of healthy women without any known complaints, and this group included 30 women, most of them from the nursing staff at Tishreen University Hospital / Oncology Department. The serum levels of vitamin D among the two groups of the study have been measured by the enzyme-linked immunosorbent assay(ELISA) technique, in parallel with the study of some clinical characteristics and routine laboratory parameters related to breast cancer and vitamin D. Results and Discussion: The results showed a clear decline in vitamin values in patients group compared with the control group, where the average values (8.31 versus 19.7 ng / mL).It has been observed that there is a relationship links breast cancer to some clinical characteristics (age, menopause, BMI, breast-feeding, outdoors activities per week, age at first birth and the number of births), that breast cancer was accompanied by age (an average of 49.34 years), post-menopause, increased BMI, lack of breast-feeding, lack of outdoors activities per week, and with the age of first birth between 19-25 years.in addition, It has been found a relationship between serum levels of vitamin D and some clinical characteristics that have been studied (age, menopause, number of births, and the style of dressing), as the decreased levels of serum vitamin D corresponded with age, post-menopause, increased number of births, and veiled dressing. Finally, considering the laboratory parameters, a relationship has been observed between serum levels of vitamin D and hormonal receptors (ER -PR -HER2 / neu) among breast cancer patients, in which the lowest serum levels of Vitamin D was accompanied by negative or weak positive estrogen receptor, and negative progesterone & HER2 / neu receptor .Conclusion: Breast cancer patients had lower serum levels of vitamin D compared to healthy women. low levels of serum vitamin D were corresponded with aging, post-menopause, increased number of births, and veiled dressing .Finally, negative hormonal receptors (estrogen, progesterone, HER2 / neu) were accompanied with the lowest serum levels of vitamin D.

إشراف وإعداد

الإشراف

سامر عاقل, فيصل رضوان

الإعداد

مضر يسري شيبان

الاقتباسات الببليوغرافية