استخدام مركبات الغلوكوز امين في تحضير مركبات سلفاميدية ودراسة خواصها وبعض تطبيقاتها

الموضوعات

علوم بحتة وطبيعية

روابط وملفات

التعريف والنوع

رقم الوثيقة

fbfe5c07-247f-4618-b680-94f53fe9e67f

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1963411_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":"احمد لبيب كيالي","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"محمد رضوان بظط","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

استخدام مركبات الغلوكوز امين في تحضير مركبات سلفاميدية ودراسة خواصها وبعض تطبيقاتها

المحتوى والصفحات

عدد الصفحات

0

ترجمة الملخص

Chemical modification reaction of Chitosan CS with the substituted sulfonile chloride compounds SC has been studied: 4-acytamido benzene sulfonile chloride ABSC and p-toluene sulfonile chloride PTSC in unselective way under various media (water or DMSO), under different temperatures, and other factors (such as of molecular ratio CS:SC, reaction time t, and the nature of participating reagent). The evaluation of sulfamide group entering reaction has been determined by comparing the FT-IR spectrum of the polymer CS and the products of the modification reaction: CS-ABSC and CS-PTSC and by the comparison of the polymers dissolution in different solvents as one of the most important characteristics in polymers description. The different factors affect the modification reaction; and the effecion of such factors on the yield of the products have been studied. The best conditions in which the reaction of sulfamide group entering to the polymer may take place whatever the media (water or DMSO) was as the following : the molecular ratio 1:2, T = (55-60)°C , t =4h and by using acetone as participating reagent, and by studying the dissolution of the products, it was observed that the dissolution of the polymer has increased when sulfamide group was introduced to chitosan in the media (water or DMSO) either in alkalin or neutral media. This character is useful for enrichment the medical applications of such polymers, the effect of such polymers as anti-oxidants was also studied, and as a result the compound CS-ABSC has anti-oxidants activity more than the compound CS-PTSC, the effect of such polymers as anti-bacterialwas also studied, and as a result the compounds containing iodine more effective. the effect of such polymers as anticoagulant was also studied, and the results were promising.

إشراف وإعداد

الإشراف

محمد رضوان بظط

الإعداد

احمد لبيب كيالي

الاقتباسات الببليوغرافية