Analyse phytochimique et l’effet anti-inflammatoire in vitro de l’algue rouge Sphaerococcus coronopifolius
F Belhakem, شاهيناز عزراويل
كلية علوم الطبيعة والحياة-جامعة عبد الحميد بن باديس مستغانم · الجزائر
الموضوعات
علوم بحتة وطبيعية
الملخص
Aquatic environments contain organisms rich in compounds endowed with biologicalactivities presenting an immense resource of new compounds with significant capacities;among these organisms are algae which are a possibly rich source of bioactive compounds.In this present work we evaluated the extraction rate, phytochemical screening and the rate ofphenolic compounds, as well as the in vitro anti-inflammatory activity of methanolic extractof the seaweed Sphaerococcus coronopifolius which is tested with two different methods:evaluation of its protective properties against thermal denaturation of BSA albumin andagainst heat-induced hemolysis of red blood cells.The results indicate a yield of crude extract is 1.6%. Phytochemical screening revealed thepresence of some bioactive substances: alkaloids, glycosides and saponins. The quantificationof total polyphenols and flavonoids gave a high value in total polyphenols 582.78 Ec μg EAG/ mg of extract compared to that of total phenols 70.544 μg EQ / mg extract.However, the results of the anti-denaturing activity of the proteins of this species areIC50=8.51±1.84μg /ml. On the other hand, the results obtained during the anti-hemolytic testby heat gave IC50=71.39±0.21μg/ml.Sphaerococcus coronopifolius species which is rich in bioactive substances has antiinflammatoryactivity
روابط وملفات
التعريف والنوع
- رقم الوثيقة
- fbf263db-46a6-4372-a34b-0be2a863511e
- رقم العقد
- 0
- نوع الوسائط
- Crawler
- نوع المحتوى
- الرسائل العلمية
- صيغة المصدر
- ماستر (LMD)
- نوع الملف
- pdf text
- أسماء الملفات
- 2144468_1.pdf
بيانات النشر
- ألقاب المؤلفين
- [{"name_ar":"F Belhakem","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"شاهيناز عزراويل","title_ar":"اعداد","title_en":"Preparation"}]
- اللغة
- French
المصدر والدورية
- اسم المصدر
- Analyse phytochimique et l’effet anti-inflammatoire in vitro de l’algue rouge Sphaerococcus coronopifolius
المحتوى والصفحات
- عدد الصفحات
- 0
- كلمات الباحثين
- Sphaerococcus coronopifolius phytochemical screening total polyphenols total flavonoids in vitro anti-inflammatory activity
إشراف وإعداد
- الإشراف
- F Belhakem
- الإعداد
- شاهيناز عزراويل
الاقتباسات الببليوغرافية
APA
MLA