Effect of Piper abyssinica and Jatropha curcas Against Experimental Haemonchus contortus Infection in Desert Goats
Samia M. A. El-Badwi, آدم داود ابابكر , نوال عبدالرحيم محمدو آدم
كلية الطب البيطري-جامعة الخرطوم · السودان
الموضوعات
طب
الملخص
The present study was run to evaluate the anthlmintic activity of Piper abyssinica andJatropha curcasagainst experimental H. contortusinfection in desert goats. All thegroups (A,B,C and D) were orally infected with a single dose of 125 third stagelarvae of H. contortus.The powdered seed of Piper abyssinica(dosed at 500 and1000mg/kg b.wt. for two consecutive days) produced 18.6 and 57.4% efficacy ratesrespect ively.The powdered seed of Jatropha curcas (dosed 250 and 500mg/kg bwt. for twoconsecutive days) produced 8.1 and 43.3% efficacy rates respectively. The powderedseed of Piper abyssinicadosages showed a significant reduction in worm numberscompared to the control group. The powdered seed of Jatropha curcasdosages alsoshowed a significant reduction in worm number when compared to the infectedcontrol.The effectiveness of powdered seeds both of Jatropha curcasand Piper abyssinicawas weaker than that produced by Ivermectin at a dose of 200 µg/kg. b.wt,comparatively the effectiveness of powdered seed of Piper abyssinicawas better thanthat of Jatropha curcas.The clinical signs inall infected groups were manifested by dullness, weakness,emaciation, diarrhoea and pale visible mucous membranes. After treatment, therewere slight histopathological changes in Piper abyssinicagroups, slight congestion inliver, small intestine, kidney, severe congestion and haemorrhage in abomasums andhaemosidrosis in the spleen.In groups that were treated with Jatropha curcasthere was slight congestion inkidney and abomusum and the spleen showed haemosiderin deposit.H. contortuseggs were detected in faces at days 17 and 18 post infection withmaximum shedding at days 19 and 25. There were decreases in Hb, PCV and RBCsin the infected control while the valuesof these haematological parameters aresignificantly increased in the treated groups of the two plants. The biochemicalalterations of infected control were characterized by reduction in total protein,albumin and iron concentrations whereasthese parameters were significantlyincreased in the treated groups of the two plants including the group that receivedIvermectin.
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- [{"name_ar":"Samia M. A. El-Badwi","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"آدم داود ابابكر ","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"نوال عبدالرحيم محمدو آدم","title_ar":"اعداد","title_en":"Preparation"}]
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- Effect of Piper abyssinica and Jatropha curcas Against Experimental Haemonchus contortus Infection in Desert Goats
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إشراف وإعداد
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- Samia M. A. El-Badwi, آدم داود ابابكر
- الإعداد
- نوال عبدالرحيم محمدو آدم
الاقتباسات الببليوغرافية
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