Assessment of Cardiac Biomarkers among newly Diagnosed cardiovascular disease Patients in Khartoum State

الموضوعات

طب

الملخص

Background: Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels, There are many diagnostic pathway to increase awareness of CVD among patients. This study was conducted to assess the activity of cardiac enzymes especially (T.CK, AST) &concentration of cTnI in all type of newly diagnostic CVD patients as cross sectional study to determine the impact of the disease on the heart.Methods: This study is a cross- sectional study conducted in sudan heart center and AL- Shaab Teaching Hospital at Khartoum state in Sudan during period of November 2016 to January 2017. Sixty newly CVD patients were selected to participate in this study, 44 of them above 50 years and 16 below 50 years cardiac enzymes measured by Mindary BA88 for (T.CK, AST), & cTnI measuredbyimmunoenzymometricassayusingTOSOHALAsystem. Results in this study there was 28 patients having CVD plus HT, and 27 patients having CVD plus DM and 15 patients having CVD plus (DM, HT) and 17 patients having CVD plus obesity. The mean level of T.CK, AST & cTnI in comparison with Reference value revealed a significance difference. The mean level of (CK, AST) and cTnI when compared between the two age group (50 years) observed a significant different. The mean level of T.CK, AST & cTnI in CVD smoker was found significantly increased when compared with non smokers CVD patients. The mean level of T.CK, AST & cTnI in CVD diabetic patient was increased when compared with non diabetic CVD patients. The mean level of T.CK, AST & cTnI in CVD hypertensive patient was when compared with non hypertensive CVD patients. As will as in Comparison between CVD alon patients as groupand CVD with other risk (DM, HT) the mean levels also observed increased significantly in the second group. Conclusions The cardiac enzymes (.TCK, AST) and cTnI is increased significantly among CVD patients and highly increased in patients with risk (DM, HT, smoker and obesity).IVﺔﺳارﺪﻟا ﺺﺨﻠﻣﺔﺳارﺪﻟا ﺔﯿﻔﻠﺧﻦﻋ ﻲﻋﻮﻟا ةدﺎﯾﺰﻟ ﺔﺼﯿﺨﺸﺘﻟا رﺎﺴﻤﻟا ﻦﻣ ﺪﯾﺪﻌﻟا كﺎﻨھ ،ﺔﯾﻮﻣﺪﻟا ﺔﯿﻋوﻷاو ﺐﻠﻘﻟا ضاﺮﻣأ ﻦﻣ ﺔﻋﻮﻤﺠﻣ ﻮھ ﻲﺋﺎﻋﻮﻟا ﻲﺒﻠﻘﻟا ضﺮﻤﻟاو ﺰﯿﻨﯾﺎﻛ ﻮﻔﺳﻮﻓ ﻦﯿﺗﺎﯾﺮﯿﻛ) ﺔﺻﺎﺧ ﺐﻠﻘﻟا تﺎﻤﯾﺰﻧإ طﺎﺸﻧ ﻢﯿﯿﻘﺘﻟ ﺔﺳارﺪﻟا هﺬھ ﺖﯾﺮﺟأ ﺪﻗو .ﻰﺿﺮﻤﻟا ىﺪﻟ ﺔﯿﺋﺎﻋﻮﻟا ﺔﯿﺒﻠﻘﻟا ضاﺮﻣﻷا ﻰﻠﻋ ضﺮﻤﻟا ﺮﯿﺛﺄﺗ ﺪﯾﺪﺤﺘﻟ ﺔﯿﻌﻄﻘﻣ ﺔﺳارد ﻦﻋ ﻢﮭﺼﯿﺨﺸﺗ ﻢﺗ ﻦﯾﺬﻟا ﻰﺿﺮﻤﻟا ﻦﻣ عﻮﻧ ﻞﻛ ﻲﻓ ىآ ﻦﯿﻧﻮﺑوﺮﺗو (ﻲﺗﺎﺗرﺎﺒﺳأ زاﺮﯿﻔﺴﻧاﺮﺗ .ﺐﻠﻘﻟاﺔﯿﺠﮭﻨﻤﻟاةﺎﺠﻨﻟا ﺰﻛﺮﻣ ﻲﻓ ﺎﮭﻠﯿﻠﺤﺗ ﻢﺗو ﺔطﺮﺸﻟا ﻰﻔﺸﺘﺴﻣ ، ﺐﻌﺸﻟا ﻰﻔﺸﺘﺴﻣ ،ﺐﻠﻘﻟا ﺰﻛﺮﻣ ﻦﻣ ﻼﻛ ﻲﻓ ﺖﯾﺮﺟأ ﺔﯿﻌﻄﻘﻣ ﺔﺳارد ﻲھ ﺔﺳارﺪﻟا هﺬھﻢﺗ ﺪﻗ ﻦﯾﺬﻟا ﻰﺿﺮﻤﻟا ﻦﻣ نﻮﺘﺳ ﻲﻓ ﺖﻤﺗ ﺪﻗو 2017ﺮﯾﺎﻨﯾ ﻰﻟإ 2016 ﺮﺒﻤﻓﻮﻧ ﻦﻣ ةﺮﺘﻔﻟا لﻼﺧ نادﻮﺴﻟا ﻲﻓ مﻮطﺮﺨﻟا ﺔﯾﻻو ﻲﻓ ﻦﻤﻗ ﺪﻗو ، ﺔﻨﺳ 50 ﻦﻣ ﻞﻗأ ﻢﮭﻨﻣ 16و ﺔﻨﺳ 50 ﻦﻣ ﺮﺜﻛأ ﻢﮭﻨﻣ 44 رﺎﻤﻋأ ﺖﻧﺎﻛ ﺪﻗو ﺔﯿﺋﺎﻋﻮﻟا ﺔﯿﺒﻠﻘﻟا ضاﺮﻣﻷﺎﺑ ﺎﺜﯾﺪﺣ ﻢﮭﺼﯿﺨﺸﺗ . يآ ﻦﯿﻧﻮﺑوﺮﺗ ﺺﺤﻔﻟ هﻮﺳﻮﺗ زﺎﮭﺟو ﻲﺗﺎﺗرﺎﺒﺳأ زاﺮﯿﻔﺴﻧاﺮﺗ و ﺰﯿﻨﯾﺎﻛ ﻮﻔﺳﻮﻓ ﻦﯿﺗﺎﯾﺮﯿﻛ ﺺﺤﻔﻟ أ ب يرﺪﻨﻣ زﺎﮭﺟ ماﺪﺨﺘﺳﺈﺑﺞﺋﺎﺘﻨﻟاﻦﯿﺑﺎﺼﻤﻟا دﺪﻋ نﺎﻛ ﺪﻗو ﺔﻨﻤﺴﻟا ضﺮﻣو يﺮﻜﺴﻟاو مﺪﻟا ﻂﻐﺿ عﺎﻔﺗرﺈﺑ ﻢﮭﺘﺑﺎﺻإ ﺐﺴﺣ ﻰﻠﻋ ﻲﺋﺎﻋﻮﻟا ﺐﻠﻘﻟا ﻰﺿﺮﻣ ﻒﯿﻨﺼﺘﺑ ﺎﻨﻤﻗ ﻦﯾﺬﻟا مأ %45 /27 يﺮﻜﺴﻟاو ، %47 /28 مﺪﻟا ﻂﻐﺿ عﺎﻔﺗرﺈﺑ ﻦﯿﺑﺎﺼﻤﻟا ﺎﻣأ ، %75 ﺔﺒﺴﻧ نﻮﻠﺜﻤﯾ ﻢھو 45ﻲﺋﺎﻋﻮﻟا ﻲﺒﻠﻘﻟا ضﺮﻤﻟﺎﺑ نﺎﻛ ﺪﺣاو نآ ﻲﻓ يﺮﻜﺴﻟاو مﺪﻟا ﻂﻐﺿ عﺎﻔﺗرإ ﻦﻣ نﻮﻧﺎﻌﯾ ﻦﯾﺬﻟا ﺐﻠﻘﻟا ﻰﺿﺮﻣ ﺎﻣأ ،%28/17 ﻢھدﺪﻋ نﺎﻛ ﺪﻘﻓ ﺔﻨﻤﺴﻟا ﻦﻣ نﻮﻧﺎﻌﯾ زاﺮﯿﻔﺴﻧاﺮﺗ و و ﺰﯿﻨﯾﺎﻛ ﻮﻔﺳﻮﻓ ﻦﯿﺗﺎﯾﺮﯿﻛ يرﺎﯿﻌﻤﻟا فاﺮﺤﻧﻹاو ﻲﺑﺎﺴﺤﻟا ﻂﺳﻮﻟا ﺔﺳارد ﺞﺋﺎﺘﻧ تﺮﮭظأ .%25 نﻮﻠﺜﻤﯾ ﻢھو 15 ﻢھدﺪﻋ ﺔﯿﺒﻠﻘﻟا تﺎﻤﯾاﺰﻧﻺﻟ ﻲﺑﺎﺴﺤﻟا ﻂﺳﻮﺘﻤﻟا ﻲﻓ ﻲﻓ ﺎظﻮﺤﻠﻣ ﺎﻓﻼﺘﺧا ﺎﻨﻈﺣﻻ .ﻲﻟاﻮﺘﻟا ﻰﻠﻋ ﺎظﻮﺤﻠﻣ ﺎﻋﺎﻔﺗرإ ىآ ﻦﯿﻧﻮﺑوﺮﺗو (ﻲﺗﺎﺗرﺎﺒﺳأ ﻰﺿﺮﻤﻟا ﺞﺋﺎﺘﻧ تﺮﮭظأو . ﺔﻄﺑﺎﻀﻟا ﺔﻋﻮﻤﺠﻤﻟا ﻲﻓ ﺎﮭﺘﻧرﺎﻘﻣ ﺪﻨﻋ ﺔﻨﺳ 50 ﻦﻣ ﺮﺜﻛأو ﺔﻨﺳ 50 ﻦﻣ ﻞﻗأ ﻰﺿﺮﻤﻠﻟ يآ ﻦﯿﻧﻮﺑوﺮﺗوةدﺎﯾز تﺮﮭظأ ىﺮﻜﺴﻟا ضﺮﻤﺑ ﻦﯿﺑﺎﺼﻤﻟا ﻰﺿﺮﻤﻟا صﺎﺨﺷﻻا ﺞﺋﺎﺘﻧ .ﻦﯿﻨﺧﺪﻤﻟا ﺮﯿﻏ ﻰﺿﺮﻤﻟا ﻊﻣ ﺔﻧرﺎﻘﻣ ﺎظﻮﺤﻠﻣ ﺎﻋﺎﻔﺗرإ ﻦﯿﻨﺧﺪﻤﻟا مﺪﻟا ﻂﻐﺿ عﺎﻔﺗرﺈﺑ ﻦﯿﺑﺎﺼﻤﻟا ﻰﺿﺮﻤﻟا ﺎﻀﯾأ ﺔﺳارﺪﻟا هﺬھ ﺖﻠﻤﺷ ﺪﻗو .يﺮﻜﺴﻟﺎﺑ ﻦﯿﺑﺎﺼﻤﻟا ﺮﯿﻏ ﻰﺿﺮﻤﻟا ﺔﻋﻮﻤﺠﻣ ﻊﻣ ﺔﻧرﺎﻘﻣ ﺔظﻮﺤﻠﻣ ﻰﺿﺮﻣ ﺞﺋﺎﺘﻧ تﺮﮭظأ اﺮﯿﺧأو .ﻦﯿﺑﺎﺼﻤﻟا ﺮﯿﻏ ﻰﺿﺮﻤﻟا ﺔﻋﻮﻤﺠﻣ ﻊﻣ ﺔﻧرﺎﻘﻣ ىآ ﻦﯿﻧﻮﺑوﺮﺗو تﺎﻤﯾﺰﻧﻹا ىﻮﺘﺴﻣ ﻲﻓ ةدﺎﯾز تﺮﮭظأ ﺪﻗو ﻂﻐﺿ عﺎﻔﺗرإو يﺮﻜﺴﻟﺎﺑ ﻦﯿﺑﺎﺼﻤﻟا ﺮﯿﻏ ﺐﻠﻘﻟا ﻰﺿﺮﻣ ﻊﻣ ﻢﮭﺘﻧرﺎﻘﻣ ﺪﻨﻋ ﺔظﻮﺤﻠﻣ ةدﺎﯾز مﺪﻟا ﻂﻐﺿ عﺎﻔﺗراو يﺮﻜﺴﻟﺎﺑ ﻦﯿﺑﺎﺼﻤﻟا ﺐﻠﻘﻟا .مﺪﻟاﺔﺻﻼﺨﻟاﺐﻠﻘﻟا ﻲﺿﺮﻣ ﻲﻓ ىآ ﻦﯿﻧﻮﺑوﺮﺗو (ﻲﺗﺎﺗرﺎﺒﺳأ زاﺮﯿﻔﺴﻧاﺮﺗ و ﺰﯿﻨﯾﺎﻛ ﻮﻔﺳﻮﻓ ﻦﯿﺗﺎﯾﺮﯿﻛ ) ﺐﻠﻘﻟا تﺎﻤﯾﺰﻧإ ﻲﻓ ﺔظﻮﺤﻠﻣ ةدﺎﯾز كﺎﻨھ ﺖﻧﺎﻛ.ضاﺮﻣﻷا ﻚﻠﺘﺑ ﻮﺑﺎﺼﯾ ﻢﻟ ﻦﯾﺬﻟاو ﻦﯿﻨﺧﺪﻤﻟا ﺮﯿﻐﺑ ﻢﮭﺘﻧرﺎﻘﻣ ﺪﻨﻋ مﺪﻟا ﻂﻐﺿ عﺎﻔﺗرإو يﺮﻜﺴﻟا ءاﺪﺑ ﻦﻣ ﻦﯿﺑﺎﺼﻣ ﻮﻧﺎﻛو ﻦﯿﻨﺧﺪﻤﻟا

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f20d19cd-cf2c-42c9-bf01-1330e5ad3403

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Crawler

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الرسائل العلمية

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[{"name_ar":"آمنة مصطفى محمد كوكو إدريس","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"صالح عبدالقادر المهدي","title_ar":"اشراف","title_en":"Supervision"}]

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اسم المصدر

Assessment of Cardiac Biomarkers among newly Diagnosed cardiovascular disease Patients in Khartoum State

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الإشراف

صالح عبدالقادر المهدي

الإعداد

آمنة مصطفى محمد كوكو إدريس

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