BCG Efficacy in Children Aged 1-7 years In A rural Area in East Nile Province

الموضوعات

طب

الملخص

Tuberculosis remains the most common single cause of death.Although BCG vaccination was introduced in 1920, yet its protective roleremains contraversial.This study was conducted in three rural areas in East NileProvince, during the period from 1st of June to 31ist of August 2003. Itwas community-based study done through house-to-house survey.The main objectives of this study were to evaluate the efficacy ofBCG vaccine and to correlate the efficacy to presence or absence of scarand some social factors. A total of 398 children (50.3% Males and 49.7%Females) aged 12 months to seven years were studied. All relevantinformations on medical, social history, history of BCG vaccinationincluding age of vaccination, symptoms suggestive of tuberculosis,physical examination including checking BCG scar and measurement ofscar size, were noted on a pre-coded questionnaire. Mantoux test wasdone and the induration was measured 72 hours later.The study showed that the predominant age group was 12-36months, which represents 42.7% of the study population; 95% were BCGvaccinated (documented by BCG scar, vaccination card or both). 73.9%of them were vaccinated in the first 3 months of age and 72% of thevaccinated had BCG scar, 39.1% of the scars measured from 2 to 5 mm,reflecting good efficacy of BCG vaccine given.68.85% of children8showed tuberculin reaction less than 5mm while only 2.5% showedreaction more than 10 mm.It was found that there is significant association between the size of the scar andtuberculin measurement supporting the fact that BCG scar is a strong indicator forvaccine efficacy.During the study 2(0.5%) cases of TB were diagnosed, their ages were 14 and18 months and both were BCG vaccinated as documented by BCG scar (in the rangeof 2-5 mm), infected TB cases represent (0.1%) of the vaccinated children, whichreflect high protection although the number of non vaccinated group was small incomparison with the vaccinated group. Social factors such as family income andnumber of persons per room did not significantly affect TB infection.The study concluded that BCG vaccination was efficient reflected in the goodimmunity documented by BCG scar and just (0.1%) TB cases among the vaccinatedgroup.

روابط وملفات

التعريف والنوع

رقم الوثيقة

ef18a0d6-1689-45ff-9628-35bd8893b116

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1639771_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":" Mai Mohamed El Hassan Mustafa ","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"Salah Ahmed Ibrahim","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

BCG Efficacy in Children Aged 1-7 years In A rural Area in East Nile Province

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

Salah Ahmed Ibrahim

الإعداد

Mai Mohamed El Hassan Mustafa

الاقتباسات الببليوغرافية