Estimation of Glomerular Filtration Rate Using Cystatin C in Diabetic Patient for Possible Development of Chronic Kidney Disease in Asmara, Eritrea

الموضوعات

طب

الملخص

Renal insufficiency in one of the most common complication in diabetic patients and in clinical practice renal function status is assessed using serum creatinine or its derivative eGFR. Recently Cystatin C is believed to be more sensitive for assessing renal function.A cross sectional descriptive study on 100 known 51 female ad 49 male diabetic patients whom are on regular follow up at diabetic clinic in Eritrea from Oct 2014 to Jan 2015. The aim of the study was to evaluate the renal function status and glycemic control of diabetic patients based on serum creatinine, Cystatin C, and HbA1C, respectively. Demographic data was analyzed using structured questioner and serum creatinine, Cystatin C, HbA1C and fasting blood glucose was determined. Data was calculated using SPSS version 19. Their age range from 12-89years old with mean (SD) 56(16.3)years and the serum creatinine ranges from 0.5-1.5 mg/dl and only 2 diabetic patients had abnormal serum creatinine, on the other hand serum Cystatin C ranges from 0.5 to 2.5mg/dl and about 50 diabetic patients with high level above normal reference value. About 47 cases has poor glycemic control (HbA1C > 7.6%). Serum creatinine based GFR had shown about 75% of the cases fall on the normal range (>90ml/min/1.73m2) However, based on serum Cystatin C only 22% of the cases fall on normal range and the rest were distributed into minimal, moderate, and high risk group stage. The study concluded that, serum Cystatin C based assessment is more sensitive and accurate to evaluate the kidney function status in diabetic patients and the study recommend that it is high time to introduce it in clinical practice to monitor the diabetic patient for possible risk and early detection of renal complication and further study can be performed in large sample size.

روابط وملفات

التعريف والنوع

رقم الوثيقة

eb84efbf-edba-41f1-bfa9-3c7352d4b97c

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

73191_1.pdf

بيانات النشر

ترجمة العنوان

قياس معدل الترشيح الكبيبي لدى المرضى المصابين بداء السكري لمعرفة إمكانية تطور أمراض الكلى المزمنة في اسمرا - اريتريا

ألقاب المؤلفين

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اللغة

English

المصدر والدورية

اسم المصدر

Estimation of Glomerular Filtration Rate Using Cystatin C in Diabetic Patient for Possible Development of Chronic Kidney Disease in Asmara, Eritrea

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

شمس الدين محمد أحمد, عمر محمد عبدالباقي

الإعداد

رستم زراتيون ولدو فوتو

الاقتباسات الببليوغرافية