Assessment of thyroid hormones and testosterone among tramadol-abusers in Gaza strip

الموضوعات

علوم بحتة وطبيعية

الملخص

Assessment of thyroid hormones and testosterone among Tramadol- Abusers in Gaza strip. Objective: The present study aimed to investigate the thyroid hormones and testosterone among Tramadol-Abusers in Gaza strip. Materials and methods: This study used case control study design performed on population of Tramadol overdosed patients, aged 15 to 35 years old who were admitted to psychiatric clinics in Gaza strip. The population consisted of 196 males (98 cases from tramadol abusers who followed before pre-detoxification and onemonth later post detoxification, and equal number healthy individuals with matching age as control. TSH, FT4, FT3 and Testosterone levels were measured. Results: There is no association between hematological parameters studied among control, tramadol abusers pre- and post-treatment (P > 0.05). The mean levels of TSH were significantly increased (P < 0.001), while FT4, FT3, and testosterone were significantly decreased in tramadol abuser before treatment compared to control. FT4 were significantly higher ( P. 0.05)., while no significant difference in the mean of TSH, FT3 and testosterone among post-treatment of tramadol abusers compared to control. TSH in tramadol abuser post-treatment were significantly decreased and the level of FT4, FT3, and testosterone in tramadol abuser post-treatment were significantly increased compared to tramadol abuser pretreatment. Pearson correlation showed positive significant correlation between in hematological profiles and hormonal levels among pre- and post-treatment of tramadol abusers. Conclusions: The mean levels of TSH were significantly increased, while FT4, FT3, and testosterone were significantly decreased in tramadol abuser before pre detoxification compared to control group. TSH in tramadol abuser postdetoxification were significantly decreased and the level of FT4, FT3, and testosterone were significantly increased compared to tramadol abuser predetoxification. Tramadol might be a risk factor for thyroid and sexual functions; further clinical research needed particularly from countries where tramadol abuse represents a problem. Keywords: Opioids, tramadol, thyroid function, testosterone, Gaza strip.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0fd8a7b0-1cff-4252-bd57-734fd60701ba

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

2103243_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":"Alaa Khaled Abu Mudalala","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"صالح نظمي موافي","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"فضل عاشور","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

Assessment of thyroid hormones and testosterone among tramadol-abusers in Gaza strip

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

صالح نظمي موافي, فضل عاشور

الإعداد

Alaa Khaled Abu Mudalala

الاقتباسات الببليوغرافية