Contribution à l’étude de l’effet antidiabétique du miel saharien et du pollen Etude in vivo chez le rat « Wistar »

الموضوعات

علوم بحتة وطبيعية

الملخص

The traditional medicine offers alternative remedies such as: medicinal plants and naturalproducts which honey is one of the most important. They possess hypoglycemic properties tocontrol or treat diabetes disease and its complications.Therefore, they are enriched bya lot of antioxidants that ensure prevention or delay ofdifferent pathologies.The study’s objective is to evaluate the antidiabetic activity of two natural products which arehoney and pollenin induced diabetes model.After 21 days of prolative treatment with euphorbia honey(10%), multifloral pollen extract(1%), and the mixture – honey and pollen- in male rats by oral pathway, the streptozotocine(STZ) in proportion of 60 mg/kg body weight is induced by intraperitonial pathway (IP) withone dose.The toxicity test ofthe selected doses represents no effect in all experimental animals.Before induction with STZ, the glucose levelis stable in all tested rats.Otherwise, after diabetes induction, the increasing level of glucose shows ahigher significancein diabetic rats (D) comparatively with control subjects (C).However, the treated rats with honey (DH) and with the mixture –honey and pollen- (DHP)have shown an hypoglycemic effect appearing in a significant low glucose level comparingwith diabetic rats (D).The histological examination shows damages in the pancreatic tissuein diabetic rats (D) withcomparison with controls (C). Whereas, the histological aspect of pancreas in diabetics treatedwith honey (DM) and treated with the mixture –honey and pollen- (DMP) seem to be veryapproach to control rats’ pancreatic aspect.The histological study of hepatic tissue in diabetic rats (D) and diabetics treated withpollen(DP) demonstrate a moderate hepatitis with lymphocytic infiltration more noticed indiabetics (D).The histology’s results reflect the results of biochemical parameters essentially blood glucoseconcentrationwhich confirmed the antidiabetic activity of the studied honey.This study shows that the euphorbia honey represents a better antidiabetic effect under theconditions of our experimentation.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0e7c50fa-30b8-43d0-ae40-926a8b73fa04

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

ماستر (LMD)

نوع الملف

pdf text

أسماء الملفات

213557_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":"Djebli Noureddine","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"Imane Abdelsadok","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

Contribution à l’étude de l’effet antidiabétique du miel saharien et du pollen Etude in vivo chez le rat « Wistar »

المحتوى والصفحات

عدد الصفحات

112

إشراف وإعداد

الإشراف

Djebli Noureddine

الإعداد

Imane Abdelsadok

الاقتباسات الببليوغرافية