Synthesis of Some Betti Base Derivatives

الموضوعات

علوم بحتة وطبيعية

الملخص

In this study, thirty one new compounds of 1- (α-aminobenzyl)-2-naphthol derivatives (Betti bases) were synthesized using two methods. In thefirst method, these compounds were synthesized via 1,3-naphthoxazines, bycondensation reaction between β-naphthol, aromatic aldehydes and primary orsecondary amines as a source of nitrogen in presence of methanol as a solvent,in the ratio of 1: 2: 1 at ambient temperature for two days. The prepared 1,3-naphthoxazines were hydrolysed in hydrochloric acid 20% with reflux for sixhours to give products known as the Betti base derivatives. In the secondmethod, Betti base derivatives were synthesized directly in one step bycondensation reaction of β- naphthol, aromatic aldehydes and ammoniasolution, in the presence of water as a solvent, in the ratio of 1: 1: 1 at ambienttemperature with stirring for one hour.Some of the synthesized Betti base derivatives that had been coupled withbenzene diazonium salts gave products in moderate to high yield as colored azodyes.The resulting compounds were purified by recrystllization and then testedby thin-layer chromatography. Physical properties of these compounds (colour,melting point, yield in grams and percentage) and spectral properties (UV, IR,1H-NMR and mass spectrometry) were measured. The results obtained revealedthat the Betti base derivatives, whether they were synthesized either through1,3-naphthoxazine or directly in one step gave identical spectral behavior andphysical properties.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0b4be390-6669-40ed-8895-b571d58c5c89

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل دكتوراة

نوع الملف

pdf text

أسماء الملفات

25343_1.pdf, 25343_2.pdf, 25343_3.pdf

بيانات النشر

ترجمة العنوان

تخليق بعض مشتقات قاعدة بيتي

ألقاب المؤلفين

[{"name_ar":"احمد الصديق محمد سعيد","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"رحمة سليمان محمد بشير","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"عزالدين الفاتح بركات","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

Synthesis of Some Betti Base Derivatives

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

احمد الصديق محمد سعيد, عزالدين الفاتح بركات

الإعداد

رحمة سليمان محمد بشير

الاقتباسات الببليوغرافية