consanguinity and other risk factors in relation to congenital malformation in live newborns at al-makassed hospital

الموضوعات

طب

الملخص

Congenital malformations occur all over the world and constitute an impenetrable core ofperinatal mortality in developed countries. In developing countries like Palestine, with thedecline of other causes of perinatal mortality, congenital malformations are acquiringimportance. The significance of congenital malformations lies not only in their contribution tomortality but also in causing disability and handicaps. Our country, with its limited financialresources for health can hardly afford to rehabilitate these children and the meager amountavailable for the same can be better utilized for salvaging normal babies by preventingcongenital malformations. The aim of this study was to investigate the association betweenconsanguinity, other risk factors, and congenital malformations. This is to provide reliableinformation to be as a baseline data for further studies, which may help in improving thequality of health care for both mothers and the newborns. A quantitative approach was adopted to investigate the prevalence and the most riskfactors of congenital malformations in the maternity department of Al-Makassed Hospital,which is a private paying institution where about 60% of the deliveries were booked earlierand 40% came as emergency cases. A retrospective study done on 5729 livebabies bornconsecutively over a period of 24 months from 1st June 2007 to May 2009. An instrument wasdeveloped specially for this study to collect the data. Descriptive statistic methods were usedand the findings were statistically interpreted using the statistical package for Social Science(SPSS). Results showed the frequency of congenital malformations was 5%. The predominantsystem involved was cardiac system. Major malformations constituted 55.3% of the total. Astatistically significant increase in the frequency of congenital malformations was observedwith decreasing gestation and birth weight. There was a significant correlation betweenmaternal factors, like previous abortions, drug intake during pregnancy period, diabetesmellitus, pre-eclampsia toxemia, and congenital malformations in the baby.The results alsoshowed that 45.9% of the cases were the product of consanguineous mating, most of themwere first cousins.The inability to discover the causes of congenital malformations is one ofthe most miserable failures of modern medicine. There is a clear need for genetic counselingservices and ante-natal diagnostic tests to be offered specially for those mothers at risk.Current legal and religious attitudes towards the options available for people at genetic riskshould be considered.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0a267d33-0dc1-42fe-a9f0-46971ccfa56d

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1696119_1.pdf

بيانات النشر

ترجمة العنوان

قرابة الأقارب وعوامل الخطر الأخرى فيما يتعلق بالتشوهات الخلقية لدى المواليد الأحياء في مستشفى المقاصد

ألقاب المؤلفين

[{"name_ar":"أحمد اسماعيل مصباح مصري","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"صدقي حمدة","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

consanguinity and other risk factors in relation to congenital malformation in live newborns at al-makassed hospital

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

صدقي حمدة

الإعداد

أحمد اسماعيل مصباح مصري

الاقتباسات الببليوغرافية