Synthesis and characterization of mono- and poly-nuclear complexes of dithiocarbamate derivative of 2-amino-5-mercapto-1,3,4-thiadiazole

الموضوعات

علوم بحتة وطبيعية

الملخص

Derivatives of 1,3,4-thiadiazole ring show biological activities against different species of microbes, therefore mono- and poly-nuclear complexes of dithiocarbamate derivatives of 2-amino-5-mercapto-1,3,4-thiadiazole (AMT), have been prepared in an attempt to show the effect of introducing two centers in the structure of the ligand (NaMTD), as well as to investigate the coordination behavior of the ligand toward both transition metals and to compare the biological activity of the complexes with that of the ligand.Dithiocarbamate derivatives of AMT (NaMTD), were prepared by condensation of CS 2 and AMT, which was itself prepared starting from thiosemicarbazide, in alcoholic sodium hydroxide solution, the product was isolated and characterized by FT-IR and U.V.-visible spectroscopy. The Pd(II) complex of  NaMTD  have been prepared using Na 2 PdCl 4 in acetone, the product (Pd-MTD) was isolated and used as precursor to prepare a series of heteropolynuclear complexes with  V 4+ , Mn 2+ , Fe 2+ , Co 2+ , Ni 2+ , Cu 2+ and Cd 2+ metal ions in DMF. Different fine crystalline, colored and stable complexes were isolated and studied using FT-IR and U.V.-visible spectroscopy, magnetic susceptibility and conductivity measurements, the metal content was determined using atomic absorption spectroscopy technique.The complexes exhibit the general formula  [(Pd-MTD) 2 ML 2 ] n     where  M = Ni 2+ , Mn 2+ and  L = H 2 O,  n = 0 M = Cu 2+   and  L =DMF,  n = 0 While the vanadyl ion show complexes of a formula (Pd-MTD) 4 VO] 2- and that  of  Fe(II)   was  [(Pd-MTD) 4 Fe] 2- .2(H 2 O).While Co 2+ and Cd 2+ have the formula [(Pd-MTD) 2 M] .2L, L = DMF for Co 2+ and  H 2 O for Cd 2+ . A number of structural phenomena have been revealed during the study. The results helped to illustrate the bonding natures between metal ions and the different donor atoms of the ligand. NaMTD was found to coordinate with Pd(II) ion through sulfur of the dithiocarbamate group and the nitrogen of the ring. The thioamide group, on the other side, was left to coordinate to the several metal ions either through sulfur atom only (in case of VO 2+ and Fe 2+ ), or chelating through nitrogen and sulfur (in case of (Ni 2+ , Cu 2+ ,Mn 2+ , Co 2+ ,  Cd 2+ ) ions.The structural formula were either octahedral for (Mn 2+ , Ni 2+ , Cu 2+ ) ions, square pyramidal (in case of  VO 2+ ion), and tetrahedral for Cd 2+ , Fe 2+ , Co 2+  ions. The antibacterial activity of the NaMTD and it ' s mono- and poly-nuclear complexes were screened against gram (+) and gram (-) bacteria.

روابط وملفات

التعريف والنوع

رقم الوثيقة

0a1a8842-4a78-479e-b644-181da52b1952

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

14348_1.pdf

بيانات النشر

ألقاب المؤلفين

[{"name_ar":" Subhi A. Al-Jibori","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"Ayad H. Jassim ","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"Salah Mohammed Faza’a","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

English

المصدر والدورية

اسم المصدر

Synthesis and characterization of mono- and poly-nuclear complexes of dithiocarbamate derivative of 2-amino-5-mercapto-1,3,4-thiadiazole

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

Subhi A. Al-Jibori, Ayad H. Jassim

الإعداد

Salah Mohammed Faza’a

الاقتباسات الببليوغرافية