تأثير التخثير الضوئي الشامل للشبكية على ثخانة اللطخة عند مرضى اعتلال الشبكية السكري التكاثري بدون وذمة لطخة هامة سريرياً

الموضوعات

طب

روابط وملفات

التعريف والنوع

رقم الوثيقة

0a14e881-4d61-407b-b78e-9d8e489dd4a2

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1963420_1.pdf

بيانات النشر

ترجمة العنوان

Effect of Panretinal Photocoagulation on the Thickness of Macula in Patients with Proliferative Diabetic Retinopathy without Clinically Significant Macular Edema

ألقاب المؤلفين

[{"name_ar":"زكريا محمد زين","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"عمـــار كيالــــي","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

تأثير التخثير الضوئي الشامل للشبكية على ثخانة اللطخة عند مرضى اعتلال الشبكية السكري التكاثري بدون وذمة لطخة هامة سريرياً

المحتوى والصفحات

عدد الصفحات

104

ترجمة الملخص

Introduction: The effectiveness of Panretinal photocoagulation (PRP) as a treatment for diabetic retinopathy (DR) was verified through a prospective study, the Diabetic Retinopathy Study, in 1976. Subsequently, from 1980 to 1985, the Early Treatment Diabetic RetinopathyStudy (ETDRS) was performed to investigate the effect of photocoagulation for macular edema and the proper treatment timing of PRP in 3,711 patients. According to the recommendations of the ETDRS group, PRP should be considered in eyes with severe DR, including those with severe nonproliferative and proliferative DR. Although PRP reduced moderate visual loss by 50% in treatment groups, it also caused significant macular edema, which is recognized as the most common cause of decreased visual acuity in diabetic eyes. In some cases, visual acuity decreases after PRP, but usually improves over several weeks. Macular edema and serous detachment of the macula has been observed after PRP, but it is not clear whether this is related to photocoagulation or if it isa coincidental finding.Purpose: The purpose of this study was to investigate changes in macular thickness after Panretinal photocoagulation (PRP) in patients with severe diabetic retinopathy (DR) without macular edema and to compare the visual acuity outcomes.Methods:This prospective cohort study included 32 patients with severe nonproliferative DR or non–high-risk proliferative DR without macular edema whose visual acuity was ≥0.5 before PRP. Sixty eyes of 32 patients with severe nonproliferative DR ornon–high-risk proliferative DR received weekly PRP treatment in 3 sessions. Macular thickness and visual acuity were measured before and at 1, 4, and 12 weeks after PRP.Results:The visual acuities were (0.08 ±0.08) logMAR units before PRP and (0.12 ±0.08) logMAR units (P < 0.05), (0.09 ± 0.08) logMAR units (P ˃0.05), and (0.08 ± 0.08) logMAR units (P ˃0.05), at 1, 4, and 12 weeks after PRP. Central macular thickness was increased at 1 (263± 27μm), 4 (245± 28μm), and 12 weeks (218± 29μm) after PRP compared with that before PRP (197± 15μm); (P < 0.05 for each).Conclusion:weekly PRP (1,200–1,800 spots) may cause a temporary drop in visual acuity in the early post laser phase and doesn't affect on the visual acuity outcomes in the most of patients with severe DR without macular edema, which was determined by clinical and optical coherence tomography examination, although mild macular thickening frequently persists.PRP appears to be a safe treatment for patients with severe diabetic retinopathy.

كلمات الباحثين

diabetic retinopathy, macular thickness, Optical coherence tomography, Panretinal photocoagulation

إشراف وإعداد

الإشراف

عمـــار كيالــــي

الإعداد

زكريا محمد زين

الاقتباسات الببليوغرافية