DRUG SURVIVAL OF DIFFERENT BIOLOGICS IN PSORIATIC PATIENTS - EVIDENCE SYNTHESIS AND HISTORICAL COHORT STUDY

الموضوعات

طب

الملخص

Biologic therapies have revolutionized the treatment of psoriasis, providing high levels of efficacy and safety. However, the choice of the appropriate therapy for each patient remains a challenge. The primary objective is to evaluate the survival rates and the all-cause discontinuation hazard ratio compared to adalimumab in treating psoriasis in all treatment series. This study is a retrospective survival analysis conducted at Hamad Medical Corporation in Qatar using the electronic medical records to collect data for patients who received biologics between Jan 2016 and Jan 2023. To compare the survival rates and all-cause discontinuation of biologics, patients with a confirmed dispensing of adalimumab, etanercept, guselkumab, infliximab, ixekizumab, secukinumab, or ustekinumab for psoriatic diagnosis. For the total treatment series model, the Kaplan- Meier survival curve was used to estimate the survival function for each biologic. In conclusion, this study has provided valuable insights into the comparative effectiveness of different biologic treatments for biologic-naive patients with psoriasis. Our findings revealed significant differences in treatment outcomes among various biologics, with some agents demonstrating superior effectiveness compared to adalimumab.

روابط وملفات

الوثيقة في المستودع الخارجي عرض في AskZad

التعريف والنوع

رقم الوثيقة: 0a14b83b-2bfa-494c-ac8f-34f2ee722c76
رقم العقد: 0
نوع الوسائط: Crawler
نوع المحتوى: الرسائل العلمية
صيغة المصدر: رسائل ماجيستير
نوع الملف: pdf text
أسماء الملفات: 798179_1.pdf

بيانات النشر

ألقاب المؤلفين: [{"name_ar":"Mohamed Izham Ibrahim","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"Nuhad T. Mohamed","title_ar":"اعداد","title_en":"Preparation"}]
اللغة: English

المصدر والدورية

اسم المصدر: DRUG SURVIVAL OF DIFFERENT BIOLOGICS IN PSORIATIC PATIENTS - EVIDENCE SYNTHESIS AND HISTORICAL COHORT STUDY

المحتوى والصفحات

عدد الصفحات: 0
كلمات الباحثين: PSORIATIC PATIENTS treatment of psoriasis Biologic therapies

إشراف وإعداد

الإشراف: Mohamed Izham Ibrahim
الإعداد: Nuhad T. Mohamed

الاقتباسات الببليوغرافية

APA

Mohamed Izham Ibrahim و Nuhad T. Mohamed. (2023). DRUG SURVIVAL OF DIFFERENT BIOLOGICS IN PSORIATIC PATIENTS - EVIDENCE SYNTHESIS AND HISTORICAL COHORT STUDY. أطروحة(رسائل ماجيستير). كلية الصيدلة-جامعة قطر. قطر.

MLA

Mohamed Izham Ibrahim و Nuhad T. Mohamed. DRUG SURVIVAL OF DIFFERENT BIOLOGICS IN PSORIATIC PATIENTS - EVIDENCE SYNTHESIS AND HISTORICAL COHORT STUDY. 2023. كلية الصيدلة-جامعة قطر، رسائل ماجيستير.