Serum Level of FSH and LH among Females with Sickle Cell Anemia in Khartoum State

الموضوعات

طب

الملخص

Sickle-cell disease (SCD), also known as sickle-cell anemia (SCA), is a group of genetically passed down blood disorders. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.This is a case control study conducted during the period from February to December2016, to determine the level of Gonadotropins (follicle stimulating hormone and Luteinizing hormone) among Sudanese female with sickle cell patients, the level of gonadotropin was estimated by using ELISA.Eighty subjects were included in this study (50 patients {40 sickler, 10traits} and 30healthy)Statistical analysis was done by using SPSS. And the result showed that follicle stimulating hormone level was significantly higher in sickler group when compared to non sickler group (5.82±4.26 Vs 3.80±2.09 .pvalue = 0.00). And luteinizing hormone did not show significant different in sickler group when compared to non sicklergroup (4.61±3.23 Vs4.52±3.43 p.value = 0.947). .The study also revealed that a significant positive correlation between follicle stimulating hormone and age.(r= 0.316,p value= 0.04) and also a significant positive correlation between luteinizing hormone and age.(r =0.405, p.value = 0.009)A significant negative correlation between follicle stimulating hormone and duration of treatment by Hydroxyurea (r =-0.447,p.value =0.045). And also show a significant negative correlation between luteinizing hormone and duration oftreatment by Hydroxyurea. (r =-0.538,p.value =0.039)In conclusion the serum level of follicle stimulating hormone is increase in patients with sickle cell disease, and luteinizing hormone is not affectedAlso there were relationship between the level of follicle stimulating hormone, luteinizing hormone and duration of treatment, eventually there was association of increasing in age and duration of sickle cell disease in patients with sickle cell disease in the increase level of follicle stimulating hormone, luteinizing hormone

روابط وملفات

التعريف والنوع

رقم الوثيقة

05689caa-45d7-49f8-81b8-fc7dac2d0a82

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

19786_1.pdf

بيانات النشر

ترجمة العنوان

مستوى هرمونى FSH و LH في مصل الدم لدي المصابات بالانيميا المنجلية في ولاية الخرطوم

ألقاب المؤلفين

[{"name_ar":" Taysser Hassan AbdElaal Elhassan ","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"مريم عباس إبراهيم","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

English

المصدر والدورية

اسم المصدر

Serum Level of FSH and LH among Females with Sickle Cell Anemia in Khartoum State

المحتوى والصفحات

عدد الصفحات

0

إشراف وإعداد

الإشراف

مريم عباس إبراهيم

الإعداد

Taysser Hassan AbdElaal Elhassan

الاقتباسات الببليوغرافية