دراسة تأثير السكري المستحدث علي النمو الوعائي البطائي في الغدد اللعابية عند الأرانب

الموضوعات

طب

روابط وملفات

التعريف والنوع

رقم الوثيقة

040fee0d-1f77-4873-9d68-4c5ff2cd1fbf

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

1962921_1.pdf

بيانات النشر

ترجمة العنوان

Investigation the affection of induced diabetes mellitus on the vascular endothelial growth in the salivary glands of rabbits

ألقاب المؤلفين

[{"name_ar":"محمد أنور خطاب","title_ar":"اعداد","title_en":"Preparation"},{"name_ar":"نبيل قوشجي","title_ar":"اشراف","title_en":"Supervision"}]

اللغة

Arabic

المصدر والدورية

اسم المصدر

دراسة تأثير السكري المستحدث علي النمو الوعائي البطائي في الغدد اللعابية عند الأرانب

المحتوى والصفحات

عدد الصفحات

109

ترجمة الملخص

Diabetes mellitus is one of the serious , wide disturbance diseases in various societies. It leads to a serious complications , in addition to many physiological and histological changes in the oral cavity . it seems that its micro-vascular complications may have a clear effects on the functions and structure of salivary glands. Aims Investigating the alterations occurred with both : proliferation index Ki67 and vascular endothelial growth factor VEGF in the salivary glands of diabetic rabbits , and compare it with normal status .Materials and methods The study sample was composed of 40 rabbit , diabetes was induced in 20 of them using Alloxan . animals were sacrificed 6 weeks later. Parotid and sub-mandibular glands were then extracted in both groups. The glands have been sectioned then stained with VEGF and Ki67 markers . the new vasculature and the proliferative cells were counted , then a compation between the control and test groups was held using Student test and Person correlation coefficient . 99 Results: The results revealed a clear affection of diabetes mellitus in increasing the expression of VEGF , by about 10% P<0.05 , the new vasclature was increased about 24% , P<0.05 . Proliferation Index Ki67 expression was increased 14% , P<0.05. in both investigated glands .Summery Diabetes mellitus leads to increasing cellular proliferation ratio and inducing a new vasculature in the salivary glands of diabetic rabbits . that is may be due to the needs of glandular tissue to compensate the lake nutrition and hypoxia for the active, saliva produce salivary glands cells

إشراف وإعداد

الإشراف

نبيل قوشجي

الإعداد

محمد أنور خطاب

الاقتباسات الببليوغرافية