Evalution Of Plasma Interleukin-8 (IL-8) Levels among Neonatal Sepsis Patients in some Selected Hospitals Khartoum State Sudan

الموضوعات

علوم بحتة وطبيعية

الملخص

One of the most important factors playing important role in neonatal sepsis pathogenesis is cytokine release, and the most effective cytokines that with proinflammatory characteristic is interleukin-8 (IL-8). This is a case-control study was aimed to evaluate the IL-8 level in Sudanese Septic neonates cases and in control subjects in Khartoum state during the period from November (2020) to May (2021). Fifty two subjects were selected convinced in this study, with age varies from 1-13 days, mean of age was 3.4± 2.6. 26 subjects were septic neonates (13 males and 13 females) as case group and 26 subjects (13 males and 13 females) as healthy control group. Venous blood sample (1ml) was collected in EDTA container from each subject.IL-8 concentration was measured using Enzyme Linked ImmunosorbentAssay(ELISA). The data was analysed using Statistical Package Social Science Programme (Version 20).The Means of IL-8 were 221±26.9, 111.1±28.7 in the case group and control group respectively. IL-8 level was significantly elevated in septic neonates than control group (P. value 0.005).In septic group there was no statistical correlation in IL-8 levels between early onset sepsis and late onset sepsis and between premature neonates and term neonates (P. value 0.66 and 0.77 respectively).Also, there was no statistical correlation between level of IL-8 with gender and age (P. value was 0.67 and 0.15 respectively). The study concluded that IL-8 concentration may be useful as a diagnostic marker for neonatal sepsis.

روابط وملفات

التعريف والنوع

رقم الوثيقة

007b3f10-d333-4dd2-b26b-8a77a310dec9

رقم العقد

0

نوع الوسائط

Crawler

نوع المحتوى

الرسائل العلمية

صيغة المصدر

رسائل ماجيستير

نوع الملف

pdf text

أسماء الملفات

2187941_1.pdf

بيانات النشر

ترجمة العنوان

تقويم مستوي المادة البلازمة الخلوية 8 وسط حديثي الولادة المصابين بالنتان الدموي في بعض المستشفيات المختارة ولاية الخرطوم السودان

ألقاب المؤلفين

[{"name_ar":"كوثر عبدالجليل محمد صالح ابراهيم","title_ar":"اشراف","title_en":"Supervision"},{"name_ar":"مودة ابوبكر هارون","title_ar":"اعداد","title_en":"Preparation"}]

اللغة

English

المصدر والدورية

اسم المصدر

Evalution Of Plasma Interleukin-8 (IL-8) Levels among Neonatal Sepsis Patients in some Selected Hospitals Khartoum State Sudan

المحتوى والصفحات

عدد الصفحات

0

كلمات الباحثين

Plasma Interleukin-8 Neonatal Sepsis

إشراف وإعداد

الإشراف

كوثر عبدالجليل محمد صالح ابراهيم

الإعداد

مودة ابوبكر هارون

الاقتباسات الببليوغرافية